Lan L - Search Results

1

Design, synthesis, and antibacterial evaluation of vancomycin-LPS binding peptide conjugates.

Shi W, Chen F, Zou X, Jiao S, Wang S, Hu Y, Lan L, Tang F, Huang W. Shi W, et al. Among authors: lan l. Bioorg Med Chem Lett. 2021 Aug 1;45:128122. doi: 10.1016/j.bmcl.2021.128122. Epub 2021 May 17. Bioorg Med Chem Lett. 2021. PMID: 34015504

2

Bioactive polyhydroxylated steroids from the Hainan soft coral Sinularia depressa Tixier-Durivault.

Liang LF, Wang XJ, Zhang HY, Liu HL, Li J, Lan LF, Zhang W, Guo YW. Liang LF, et al. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1334-7. doi: 10.1016/j.bmcl.2012.12.087. Epub 2013 Jan 4. Bioorg Med Chem Lett. 2013. PMID: 23357636

3

Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase.

Zhang J, Liu H, Zhu K, Gong S, Dramsi S, Wang YT, Li J, Chen F, Zhang R, Zhou L, Lan L, Jiang H, Schneewind O, Luo C, Yang CG. Zhang J, et al. Among authors: lan l. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13517-22. doi: 10.1073/pnas.1408601111. Epub 2014 Sep 2. Proc Natl Acad Sci U S A. 2014. PMID: 25197057 Free PMC article.

4

Metabolic sensor governing bacterial virulence in Staphylococcus aureus.

Ding Y, Liu X, Chen F, Di H, Xu B, Zhou L, Deng X, Wu M, Yang CG, Lan L. Ding Y, et al. Among authors: lan l. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):E4981-90. doi: 10.1073/pnas.1411077111. Epub 2014 Nov 3. Proc Natl Acad Sci U S A. 2014. PMID: 25368190 Free PMC article.

5

The Crc protein participates in down-regulation of the Lon gene to promote rhamnolipid production and rhl quorum sensing in Pseudomonas aeruginosa.

Yang N, Ding S, Chen F, Zhang X, Xia Y, Di H, Cao Q, Deng X, Wu M, Wong CC, Tian XX, Yang CG, Zhao J, Lan L. Yang N, et al. Among authors: lan l. Mol Microbiol. 2015 May;96(3):526-47. doi: 10.1111/mmi.12954. Epub 2015 Feb 26. Mol Microbiol. 2015. PMID: 25641250 Free article.

6

Small-molecule targeting of a diapophytoene desaturase inhibits S. aureus virulence.

Chen F, Di H, Wang Y, Cao Q, Xu B, Zhang X, Yang N, Liu G, Yang CG, Xu Y, Jiang H, Lian F, Zhang N, Li J, Lan L. Chen F, et al. Among authors: lan l. Nat Chem Biol. 2016 Mar;12(3):174-9. doi: 10.1038/nchembio.2003. Epub 2016 Jan 18. Nat Chem Biol. 2016. PMID: 26780405

7

Discovery of Potent Benzofuran-Derived Diapophytoene Desaturase (CrtN) Inhibitors with Enhanced Oral Bioavailability for the Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections.

Wang Y, Chen F, Di H, Xu Y, Xiao Q, Wang X, Wei H, Lu Y, Zhang L, Zhu J, Sheng C, Lan L, Li J. Wang Y, et al. Among authors: lan l. J Med Chem. 2016 Apr 14;59(7):3215-30. doi: 10.1021/acs.jmedchem.5b01984. Epub 2016 Apr 5. J Med Chem. 2016. PMID: 26999509

8

Discovery of Benzocycloalkane Derivatives Efficiently Blocking Bacterial Virulence for the Treatment of Methicillin-Resistant S. aureus (MRSA) Infections by Targeting Diapophytoene Desaturase (CrtN).

Wang Y, Di H, Chen F, Xu Y, Xiao Q, Wang X, Wei H, Lu Y, Zhang L, Zhu J, Lan L, Li J. Wang Y, et al. Among authors: lan l. J Med Chem. 2016 May 26;59(10):4831-48. doi: 10.1021/acs.jmedchem.6b00122. Epub 2016 May 9. J Med Chem. 2016. PMID: 27139780

9

Novel Inhibitors of Staphyloxanthin Virulence Factor in Comparison with Linezolid and Vancomycin versus Methicillin-Resistant, Linezolid-Resistant, and Vancomycin-Intermediate Staphylococcus aureus Infections in Vivo.

Ni S, Wei H, Li B, Chen F, Liu Y, Chen W, Xu Y, Qiu X, Li X, Lu Y, Liu W, Hu L, Lin D, Wang M, Zheng X, Mao F, Zhu J, Lan L, Li J. Ni S, et al. Among authors: lan l. J Med Chem. 2017 Oct 12;60(19):8145-8159. doi: 10.1021/acs.jmedchem.7b00949. Epub 2017 Sep 21. J Med Chem. 2017. PMID: 28880552

10

Design, synthesis and structure-activity relationship evaluation of novel LpxC inhibitors as Gram-negative antibacterial agents.

Ding S, Dai RY, Wang WK, Cao Q, Lan LF, Zhou XL, Yang YS. Ding S, et al. Bioorg Med Chem Lett. 2018 Jan 15;28(2):94-102. doi: 10.1016/j.bmcl.2017.12.005. Epub 2017 Dec 5. Bioorg Med Chem Lett. 2018. PMID: 29233653

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