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Spatial aspects of oncogenic signalling determine the response to combination therapy in slice explants from Kras-driven lung tumours.
Närhi K, Nagaraj AS, Parri E, Turkki R, van Duijn PW, Hemmes A, Lahtela J, Uotinen V, Mäyränpää MI, Salmenkivi K, Räsänen J, Linder N, Trapman J, Rannikko A, Kallioniemi O, Af Hällström TM, Lundin J, Sommergruber W, Anders S, Verschuren EW. Närhi K, et al. J Pathol. 2018 May;245(1):101-113. doi: 10.1002/path.5059. Epub 2018 Apr 2. J Pathol. 2018. PMID: 29443392 Free PMC article.
Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices.
Davies EJ, Dong M, Gutekunst M, Närhi K, van Zoggel HJ, Blom S, Nagaraj A, Metsalu T, Oswald E, Erkens-Schulze S, Delgado San Martin JA, Turkki R, Wedge SR, af Hällström TM, Schueler J, van Weerden WM, Verschuren EW, Barry ST, van der Kuip H, Hickman JA. Davies EJ, et al. Among authors: narhi k. Sci Rep. 2015 Dec 9;5:17187. doi: 10.1038/srep17187. Sci Rep. 2015. PMID: 26647838 Free PMC article.
Protocols and characterization data for 2D, 3D, and slice-based tumor models from the PREDECT project.
de Hoogt R, Estrada MF, Vidic S, Davies EJ, Osswald A, Barbier M, Santo VE, Gjerde K, van Zoggel HJAA, Blom S, Dong M, Närhi K, Boghaert E, Brito C, Chong Y, Sommergruber W, van der Kuip H, van Weerden WM, Verschuren EW, Hickman J, Graeser R. de Hoogt R, et al. Among authors: narhi k. Sci Data. 2017 Nov 21;4:170170. doi: 10.1038/sdata.2017.170. Sci Data. 2017. PMID: 29160867 Free PMC article.
23 results