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mRNA therapy restores euglycemia and prevents liver tumors in murine model of glycogen storage disease.
Cao J, Choi M, Guadagnin E, Soty M, Silva M, Verzieux V, Weisser E, Markel A, Zhuo J, Liang S, Yin L, Frassetto A, Graham AR, Burke K, Ketova T, Mihai C, Zalinger Z, Levy B, Besin G, Wolfrom M, Tran B, Tunkey C, Owen E, Sarkis J, Dousis A, Presnyak V, Pepin C, Zheng W, Ci L, Hard M, Miracco E, Rice L, Nguyen V, Zimmer M, Rajarajacholan U, Finn PF, Mithieux G, Rajas F, Martini PGV, Giangrande PH. Cao J, et al. Among authors: rajas f. Nat Commun. 2021 May 25;12(1):3090. doi: 10.1038/s41467-021-23318-2. Nat Commun. 2021. PMID: 34035281 Free PMC article.
Glucose utilization is suppressed in the gut of insulin-resistant high fat-fed rats and is restored by metformin.
Mithieux G, Rajas F, Zitoun C. Mithieux G, et al. Among authors: rajas f. Biochem Pharmacol. 2006 Jul 14;72(2):198-203. doi: 10.1016/j.bcp.2006.04.020. Epub 2006 May 2. Biochem Pharmacol. 2006. Corrected and republished in: Biochem Pharmacol. 2006 Dec 15;72(12):1757-62. doi: 10.1016/j.bcp.2006.08.020 PMID: 16737687 Corrected and republished.
82 results