Fan C - Search Results

1

Synthesis and Pharmacological Evaluation of Tetrahydro-γ-carboline Derivatives as Potent Anti-inflammatory Agents Targeting Cyclic GMP-AMP Synthase.

Tan J, Wu B, Chen T, Fan C, Zhao J, Xiong C, Feng C, Xiao R, Ding C, Tang W, Zhang A. Tan J, et al. Among authors: fan c. J Med Chem. 2021 Jun 10;64(11):7667-7690. doi: 10.1021/acs.jmedchem.1c00398. Epub 2021 May 27. J Med Chem. 2021. PMID: 34044539

2

Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity.

Li H, Fan C, Feng C, Wu Y, Lu H, He P, Yang X, Zhu F, Qi Q, Gao Y, Zuo J, Tang W. Li H, et al. Among authors: fan c. Br J Pharmacol. 2019 Jul;176(13):2209-2226. doi: 10.1111/bph.14667. Epub 2019 May 17. Br J Pharmacol. 2019. PMID: 30883697 Free PMC article.

3

RIPK1 inhibitor ameliorates colitis by directly maintaining intestinal barrier homeostasis and regulating following IECs-immuno crosstalk.

Lu H, Li H, Fan C, Qi Q, Yan Y, Wu Y, Feng C, Wu B, Gao Y, Zuo J, Tang W. Lu H, et al. Among authors: fan c. Biochem Pharmacol. 2020 Feb;172:113751. doi: 10.1016/j.bcp.2019.113751. Epub 2019 Dec 16. Biochem Pharmacol. 2020. PMID: 31837309

4

DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models.

Zhang Z, Wu Y, Wu B, Qi Q, Li H, Lu H, Fan C, Feng C, Zuo J, Niu L, Tang W. Zhang Z, et al. Among authors: fan c. Arthritis Res Ther. 2019 Dec 16;21(1):290. doi: 10.1186/s13075-019-2074-9. Arthritis Res Ther. 2019. PMID: 31842999 Free PMC article.

5

Protective role of berberine on ulcerative colitis through modulating enteric glial cells-intestinal epithelial cells-immune cells interactions.

Li H, Fan C, Lu H, Feng C, He P, Yang X, Xiang C, Zuo J, Tang W. Li H, et al. Among authors: fan c. Acta Pharm Sin B. 2020 Mar;10(3):447-461. doi: 10.1016/j.apsb.2019.08.006. Epub 2019 Sep 5. Acta Pharm Sin B. 2020. PMID: 32140391 Free PMC article.

6

DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling.

Li H, Li J, Zhang X, Feng C, Fan C, Yang X, Zhang R, Zhu F, Zhou Y, Xu Y, Liu H, Tang W. Li H, et al. Among authors: fan c. Biochem Pharmacol. 2020 Jul;177:113958. doi: 10.1016/j.bcp.2020.113958. Epub 2020 Apr 3. Biochem Pharmacol. 2020. PMID: 32251674

7

Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way.

Wu Y, Wu B, Zhang Z, Lu H, Fan C, Qi Q, Gao Y, Li H, Feng C, Zuo J, Tang W. Wu Y, et al. Among authors: fan c. FASEB J. 2020 Jun;34(6):8028-8043. doi: 10.1096/fj.202000313RR. Epub 2020 Apr 17. FASEB J. 2020. PMID: 32301543

8

Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis.

Li H, Feng C, Fan C, Yang Y, Yang X, Lu H, Lu Q, Zhu F, Xiang C, Zhang Z, He P, Zuo J, Tang W. Li H, et al. Among authors: fan c. Cell Death Dis. 2020 Apr 24;11(4):271. doi: 10.1038/s41419-020-2470-8. Cell Death Dis. 2020. PMID: 32332711 Free PMC article.

9

Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment.

Zhang R, Li H, Zhang X, Li J, Su H, Lu Q, Dong G, Dou H, Fan C, Gu Z, Mu Q, Tang W, Xu Y, Liu H. Zhang R, et al. Among authors: fan c. Eur J Med Chem. 2021 Feb 5;211:113004. doi: 10.1016/j.ejmech.2020.113004. Epub 2020 Nov 7. Eur J Med Chem. 2021. PMID: 33218684

10

Heme supplementation ameliorates lupus nephritis through rectifying the disorder of splenocytes and alleviating renal inflammation and oxidative damage.

Wu B, Wu Y, Fan C, Feng C, Wang H, Bai F, Zuo J, Tang W. Wu B, et al. Among authors: fan c. Int Immunopharmacol. 2021 May;94:107482. doi: 10.1016/j.intimp.2021.107482. Epub 2021 Feb 24. Int Immunopharmacol. 2021. PMID: 33639567

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