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The interaction between alpha 7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α represents a new antinociceptive signaling pathway in mice.
Donvito G, Bagdas D, Toma W, Rahimpour E, Jackson A, Meade JA, AlSharari S, Kulkarni AR, Ivy Carroll F, Lichtman AH, Papke RL, Thakur GA, Imad Damaj M. Donvito G, et al. Exp Neurol. 2017 Sep;295:194-201. doi: 10.1016/j.expneurol.2017.06.014. Epub 2017 Jun 9. Exp Neurol. 2017. PMID: 28606623 Free PMC article.
Reduced intraepidermal nerve fibre density, glial activation, and sensory changes in HIV type-1 Tat-expressing female mice: involvement of Tat during early stages of HIV-associated painful sensory neuropathy.
Wodarski R, Bagdas D, Paris JJ, Pheby T, Toma W, Xu R, Damaj MI, Knapp PE, Rice ASC, Hauser KF. Wodarski R, et al. Pain Rep. 2018 May 14;3(3):e654. doi: 10.1097/PR9.0000000000000654. eCollection 2018 May. Pain Rep. 2018. PMID: 29922746 Free PMC article.
The α7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal.
Toma W, Kyte SL, Bagdas D, Jackson A, Meade JA, Rahman F, Chen ZJ, Del Fabbro E, Cantwell L, Kulkarni A, Thakur GA, Papke RL, Bigbee JW, Gewirtz DA, Damaj MI. Toma W, et al. Exp Neurol. 2019 Oct;320:113010. doi: 10.1016/j.expneurol.2019.113010. Epub 2019 Jul 9. Exp Neurol. 2019. PMID: 31299179 Free PMC article.
27 results