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Antibodies Against Angiotensin II Receptor Type 1 and Endothelin A Receptor Are Associated With an Unfavorable COVID19 Disease Course.
Miedema J, Schreurs M, van der Sar-van der Brugge S, Paats M, Baart S, Bakker M, Hoek R, Dik WA, Endeman H, Van Der Velden V, van Gammeren A, Ermens A, Aerts JG, Thüsen JV. Miedema J, et al. Front Immunol. 2021 May 13;12:684142. doi: 10.3389/fimmu.2021.684142. eCollection 2021. Front Immunol. 2021. PMID: 34054876 Free PMC article.
Enhanced Bruton's tyrosine kinase in B-cells and autoreactive IgA in patients with idiopathic pulmonary fibrosis.
Heukels P, van Hulst JAC, van Nimwegen M, Boorsma CE, Melgert BN, von der Thusen JH, van den Blink B, Hoek RAS, Miedema JR, Neys SFH, Corneth OBJ, Hendriks RW, Wijsenbeek MS, Kool M. Heukels P, et al. Among authors: miedema jr. Respir Res. 2019 Oct 24;20(1):232. doi: 10.1186/s12931-019-1195-7. Respir Res. 2019. PMID: 31651327 Free PMC article.
Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection.
Gharbharan A, Jordans CCE, GeurtsvanKessel C, den Hollander JG, Karim F, Mollema FPN, Stalenhoef-Schukken JE, Dofferhoff A, Ludwig I, Koster A, Hassing RJ, Bos JC, van Pottelberge GR, Vlasveld IN, Ammerlaan HSM, van Leeuwen-Segarceanu EM, Miedema J, van der Eerden M, Schrama TJ, Papageorgiou G, Te Boekhorst P, Swaneveld FH, Mueller YM, Schreurs MWJ, van Kampen JJA, Rockx B, Okba NMA, Katsikis PD, Koopmans MPG, Haagmans BL, Rokx C, Rijnders BJA. Gharbharan A, et al. Among authors: miedema j. Nat Commun. 2021 May 27;12(1):3189. doi: 10.1038/s41467-021-23469-2. Nat Commun. 2021. PMID: 34045486 Free PMC article. Clinical Trial.
Altered fibrin network structure and fibrinolysis in intensive care unit patients with COVID-19, not entirely explaining the increased risk of thrombosis.
de Vries JJ, Visser C, Geers L, Slotman JA, van Kleef ND, Maas C, Bax HI, Miedema JR, van Gorp ECM, Goeijenbier M, van den Akker JPC, Endeman H, Rijken DC, Kruip MJHA, de Maat MPM. de Vries JJ, et al. Among authors: miedema jr. J Thromb Haemost. 2022 Jun;20(6):1412-1420. doi: 10.1111/jth.15708. Epub 2022 Apr 1. J Thromb Haemost. 2022. PMID: 35316570 Free PMC article.
Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients.
Millat-Martinez P, Gharbharan A, Alemany A, Rokx C, Geurtsvankessel C, Papageorgiou G, van Geloven N, Jordans C, Groeneveld G, Swaneveld F, van der Schoot E, Corbacho-Monné M, Ouchi D, Piccolo Ferreira F, Malchair P, Videla S, García García V, Ruiz-Comellas A, Ramírez-Morros A, Rodriguez Codina J, Amado Simon R, Grifols JR, Blanco J, Blanco I, Ara J, Bassat Q, Clotet B, Baro B, Troxel A, Zwaginga JJ, Mitjà O, Rijnders BJA; CoV-Early study group; COnV-ert study group. Millat-Martinez P, et al. Nat Commun. 2022 May 11;13(1):2583. doi: 10.1038/s41467-022-29911-3. Nat Commun. 2022. PMID: 35546145 Free PMC article.
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