Zhuang W - Search Results

1

Discovery of 1,5-Dihydro-4H-imidazol-4-one Derivatives as Potent, Selective Antagonists of CXC Chemokine Receptor 2.

Che J, Wang Z, Shen Z, Zhuang W, Ying H, Hu Y, Hu Y, Xie X, Dong X. Che J, et al. Among authors: zhuang w. ACS Med Chem Lett. 2021 Apr 8;12(5):836-845. doi: 10.1021/acsmedchemlett.1c00113. eCollection 2021 May 13. ACS Med Chem Lett. 2021. PMID: 34055234 Free PMC article.

2

Discovery of phenyl-linked symmetric small molecules as inhibitors of the programmed cell death-1/programmed cell death-ligand 1 interaction.

Wu Y, Zhang Y, Guo Y, Pan Z, Zhong S, Jin X, Zhuang W, Chen S, Gao J, Huang W, Dong X, Che J. Wu Y, et al. Among authors: zhuang w. Eur J Med Chem. 2021 Nov 5;223:113637. doi: 10.1016/j.ejmech.2021.113637. Epub 2021 Jun 11. Eur J Med Chem. 2021. PMID: 34147746

3

Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells.

Qu B, Xu Y, Lu Y, Zhuang W, Jin X, Shi Q, Yan S, Guo Y, Shen Z, Che J, Wu Y, Tong L, Dong X, Yang H. Qu B, et al. Among authors: zhuang w. Eur J Med Chem. 2022 May 5;235:114257. doi: 10.1016/j.ejmech.2022.114257. Epub 2022 Mar 26. Eur J Med Chem. 2022. PMID: 35367710

4

Identification of Novel Covalent XPO1 Inhibitors Based on a Hybrid Virtual Screening Strategy.

Shen Z, Zhuang W, Li K, Guo Y, Qu B, Chen S, Gao J, Liu J, Xu L, Dong X, Che J, Li Q. Shen Z, et al. Among authors: zhuang w. Molecules. 2022 Apr 14;27(8):2543. doi: 10.3390/molecules27082543. Molecules. 2022. PMID: 35458742 Free PMC article.

5

Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton's Tyrosine Kinase for the Treatment of Lymphoma.

Zhang J, Che J, Luo X, Wu M, Kan W, Jin Y, Wang H, Pang A, Li C, Huang W, Zeng S, Zhuang W, Wu Y, Xu Y, Zhou Y, Li J, Dong X. Zhang J, et al. Among authors: zhuang w. J Med Chem. 2022 Jul 14;65(13):9096-9125. doi: 10.1021/acs.jmedchem.2c00324. Epub 2022 Jun 7. J Med Chem. 2022. PMID: 35671249

6

Peripheral immune cell profiling of double-hit lymphoma by mass cytometry.

Lei T, Wu G, Xu Y, Zhuang W, Lu J, Han S, Zhuang Y, Dong X, Yang H. Lei T, et al. Among authors: zhuang w, zhuang y. BMC Cancer. 2023 Feb 23;23(1):184. doi: 10.1186/s12885-023-10657-0. BMC Cancer. 2023. PMID: 36823603 Free PMC article.

7

Rational Identification of Novel Antibody-Drug Conjugate with High Bystander Killing Effect against Heterogeneous Tumors.

Guo Y, Shen Z, Zhao W, Lu J, Song Y, Shen L, Lu Y, Wu M, Shi Q, Zhuang W, Qiu Y, Sheng J, Zhou Z, Fang L, Che J, Dong X. Guo Y, et al. Among authors: zhuang w. Adv Sci (Weinh). 2024 Apr;11(13):e2306309. doi: 10.1002/advs.202306309. Epub 2024 Jan 25. Adv Sci (Weinh). 2024. PMID: 38269648 Free PMC article.

8

Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expression.

Lu Y, Gao J, Wang P, Chen H, He X, Luo M, Guo Y, Li L, Zhuang W, Zhang B, Lin N, Li J, Zhou Y, Dong X, Che J. Lu Y, et al. Among authors: zhuang w. Eur J Med Chem. 2024 Jun 5;272:116468. doi: 10.1016/j.ejmech.2024.116468. Epub 2024 May 5. Eur J Med Chem. 2024. PMID: 38718626

9

Discovery of New Phenyltetrazolium Derivatives as Ferroptosis Inhibitors for Treating Ischemic Stroke: An Example Development from Free Radical Scavengers.

Lu Y, Shen Z, Xu Y, Lin H, Shen L, Jin Y, Guo Y, Lu J, Li L, Zhuang Y, Jin Y, Zhuang W, Huang W, Dong X, Dai H, Che J. Lu Y, et al. Among authors: zhuang w, zhuang y. J Med Chem. 2024 Jul 25;67(14):11712-11731. doi: 10.1021/acs.jmedchem.4c00211. Epub 2024 Jul 12. J Med Chem. 2024. PMID: 38996382

10

WITHDRAWN: Effects of cancer-associated point mutations on the structure, function, and stability of succinate dehydrogenase A.

Cao ZF, Ni N, Zhuang W, Ye F, Wu Y, Qiu J, Wu Y, Sheng Q, Ou WB. Cao ZF, et al. Among authors: zhuang w. J Biol Chem. 2019 Feb 6:jbc.RA118.006266. doi: 10.1074/jbc.RA118.006266. Online ahead of print. J Biol Chem. 2019. PMID: 30728243 Free article.

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