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Page 1
DNA Topoisomerase 3α Is Involved in Homologous Recombination Repair and Replication Stress Response in Trypanosoma cruzi.
Costa-Silva HM, Resende BC, Umaki ACS, Prado W, da Silva MS, Virgílio S, Macedo AM, Pena SDJ, Tahara EB, Tosi LRO, Elias MC, Andrade LO, Reis-Cunha JL, Franco GR, Fragoso SP, Machado CR. Costa-Silva HM, et al. Among authors: fragoso sp. Front Cell Dev Biol. 2021 May 13;9:633195w. doi: 10.3389/fcell.2021.633195. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34055812 Free PMC article.
In vitro metacyclogenesis of Trypanosoma cruzi induced by starvation correlates with a transient adenylyl cyclase stimulation as well as with a constitutive upregulation of adenylyl cyclase expression.
Hamedi A, Botelho L, Britto C, Fragoso SP, Umaki AC, Goldenberg S, Bottu G, Salmon D. Hamedi A, et al. Among authors: fragoso sp. Mol Biochem Parasitol. 2015 Mar-Apr;200(1-2):9-18. doi: 10.1016/j.molbiopara.2015.04.002. Epub 2015 Apr 23. Mol Biochem Parasitol. 2015. PMID: 25912925 Free article.
Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi.
Pavani RS, da Silva MS, Fernandes CA, Morini FS, Araujo CB, Fontes MR, Sant'Anna OA, Machado CR, Cano MI, Fragoso SP, Elias MC. Pavani RS, et al. Among authors: fragoso sp. PLoS Negl Trop Dis. 2016 Dec 16;10(12):e0005181. doi: 10.1371/journal.pntd.0005181. eCollection 2016 Dec. PLoS Negl Trop Dis. 2016. PMID: 27984589 Free PMC article.
The Influence of Recombinational Processes to Induce Dormancy in Trypanosoma cruzi.
Resende BC, Oliveira ACS, Guañabens ACP, Repolês BM, Santana V, Hiraiwa PM, Pena SDJ, Franco GR, Macedo AM, Tahara EB, Fragoso SP, Andrade LO, Machado CR. Resende BC, et al. Among authors: fragoso sp. Front Cell Infect Microbiol. 2020 Jan 28;10:5. doi: 10.3389/fcimb.2020.00005. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32117793 Free PMC article.
H2B.V demarcates divergent strand-switch regions, some tDNA loci, and genome compartments in Trypanosoma cruzi and affects parasite differentiation and host cell invasion.
Rosón JN, Vitarelli MO, Costa-Silva HM, Pereira KS, Pires DDS, Lopes LS, Cordeiro B, Kraus AJ, Cruz KNT, Calderano SG, Fragoso SP, Siegel TN, Elias MC, da Cunha JPC. Rosón JN, et al. Among authors: fragoso sp. PLoS Pathog. 2022 Feb 18;18(2):e1009694. doi: 10.1371/journal.ppat.1009694. eCollection 2022 Feb. PLoS Pathog. 2022. PMID: 35180281 Free PMC article.
DNA lesions that block transcription induce the death of Trypanosoma cruzi via ATR activation, which is dependent on the presence of R-loops.
Mendes IC, Dos Reis Bertoldo W, Miranda-Junior AS, Assis AV, Repolês BM, Ferreira WRR, Chame DF, Souza DL, Pavani RS, Macedo AM, Franco GR, Serra E, Perdomo V, Menck CFM, da Silva Leandro G, Fragoso SP, Barbosa Elias MCQ, Machado CR. Mendes IC, et al. Among authors: fragoso sp. DNA Repair (Amst). 2024 Sep;141:103726. doi: 10.1016/j.dnarep.2024.103726. Epub 2024 Jul 27. DNA Repair (Amst). 2024. PMID: 39096697
57 results