McKeon JE - Search Results

1

ALS-linked PFN1 variants exhibit loss and gain of functions in the context of formin-induced actin polymerization.

Schmidt EJ, Funes S, McKeon JE, Morgan BR, Boopathy S, O'Connor LC, Bilsel O, Massi F, Jégou A, Bosco DA. Schmidt EJ, et al. Among authors: mckeon je. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024605118. doi: 10.1073/pnas.2024605118. Proc Natl Acad Sci U S A. 2021. PMID: 34074767 Free PMC article.

2

ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation.

Sama RR, Fallini C, Gatto R, McKeon JE, Song Y, Rotunno MS, Penaranda S, Abdurakhmanov I, Landers JE, Morfini G, Brady ST, Bosco DA. Sama RR, et al. Among authors: mckeon je. Sci Rep. 2017 Mar 8;7(1):115. doi: 10.1038/s41598-017-00091-1. Sci Rep. 2017. PMID: 28273913 Free PMC article.

3

Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.

Peters OM, Cabrera GT, Tran H, Gendron TF, McKeon JE, Metterville J, Weiss A, Wightman N, Salameh J, Kim J, Sun H, Boylan KB, Dickson D, Kennedy Z, Lin Z, Zhang YJ, Daughrity L, Jung C, Gao FB, Sapp PC, Horvitz HR, Bosco DA, Brown SP, de Jong P, Petrucelli L, Mueller C, Brown RH Jr. Peters OM, et al. Among authors: mckeon je. Neuron. 2015 Dec 2;88(5):902-909. doi: 10.1016/j.neuron.2015.11.018. Neuron. 2015. PMID: 26637797 Free PMC article.

4

Gap junction assembly in the preimplantation mouse conceptus is independent of microtubules, microfilaments, cell flattening, and cytokinesis.

Kidder GM, Rains J, McKeon J. Kidder GM, et al. Proc Natl Acad Sci U S A. 1987 Jun;84(11):3718-22. doi: 10.1073/pnas.84.11.3718. Proc Natl Acad Sci U S A. 1987. PMID: 3473479 Free PMC article.

5

Pharmacophore Establishment and Optimization of Saturated 1,6-Naphthyridine-Fused Quinazolinones that Inhibit Meningoencephalitis-Causing Naegleria fowleri.

Lish MS, McKeon JEM, Palmentiero CM, Pomeroy JM, Roster CP, Guzei IA, Morris JC, Golden JE. Lish MS, et al. Among authors: mckeon jem. J Med Chem. 2024 Oct 24;67(20):18265-18289. doi: 10.1021/acs.jmedchem.4c01630. Epub 2024 Oct 15. J Med Chem. 2024. PMID: 39402986

6

Parkin-mediated K63-polyubiquitination targets ubiquitin C-terminal hydrolase L1 for degradation by the autophagy-lysosome system.

McKeon JE, Sha D, Li L, Chin LS. McKeon JE, et al. Cell Mol Life Sci. 2015 May;72(9):1811-24. doi: 10.1007/s00018-014-1781-2. Epub 2014 Nov 18. Cell Mol Life Sci. 2015. PMID: 25403879 Free PMC article.

7

25-Hydroxyvitamin D depletion does not exacerbate MPTP-induced dopamine neuron damage in mice.

Dean ED, Mexas LM, Cápiro NL, McKeon JE, DeLong MR, Pennell KD, Doorn JA, Tangpricha V, Miller GW, Evatt ML. Dean ED, et al. Among authors: mckeon je. PLoS One. 2012;7(7):e39227. doi: 10.1371/journal.pone.0039227. Epub 2012 Jul 2. PLoS One. 2012. PMID: 22768297 Free PMC article.

8

Assessment of general anaesthetic cytotoxicity in murine cortical neurones in dissociated culture.

Campbell LL, Tyson JA, Stackpole EE, Hokenson KE, Sherrill H, McKeon JE, Kim SA, Edmands SD, Suarez C, Hall AC. Campbell LL, et al. Among authors: mckeon je. Toxicology. 2011 Apr 28;283(1):1-7. doi: 10.1016/j.tox.2011.01.014. Epub 2011 Jan 26. Toxicology. 2011. PMID: 21277931

9

Studies related to the biosynthesis of prodigiosin in Serratia marcescens.

WASSERMAN HH, McKEON JE, SANTER UV. WASSERMAN HH, et al. Among authors: mckeon je. Biochem Biophys Res Commun. 1960 Aug;3:146-9. doi: 10.1016/0006-291x(60)90211-4. Biochem Biophys Res Commun. 1960. PMID: 13843029 No abstract available.

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