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Discovery of a cooperative mode of inhibiting RIPK1 kinase.
Meng H, Wu G, Zhao X, Wang A, Li D, Tong Y, Jin T, Cao Y, Shan B, Hu S, Li Y, Pan L, Tian X, Wu P, Peng C, Yuan J, Li G, Tan L, Wang Z, Li Y. Meng H, et al. Among authors: pan l. Cell Discov. 2021 Jun 1;7(1):41. doi: 10.1038/s41421-021-00278-x. Cell Discov. 2021. PMID: 34075030 Free PMC article.
Chaperone-mediated autophagy degrades mutant p53.
Vakifahmetoglu-Norberg H, Kim M, Xia HG, Iwanicki MP, Ofengeim D, Coloff JL, Pan L, Ince TA, Kroemer G, Brugge JS, Yuan J. Vakifahmetoglu-Norberg H, et al. Among authors: pan l. Genes Dev. 2013 Aug 1;27(15):1718-30. doi: 10.1101/gad.220897.113. Genes Dev. 2013. PMID: 23913924 Free PMC article.
Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death.
Xia HG, Najafov A, Geng J, Galan-Acosta L, Han X, Guo Y, Shan B, Zhang Y, Norberg E, Zhang T, Pan L, Liu J, Coloff JL, Ofengeim D, Zhu H, Wu K, Cai Y, Yates JR, Zhu Z, Yuan J, Vakifahmetoglu-Norberg H. Xia HG, et al. Among authors: pan l. J Cell Biol. 2015 Aug 31;210(5):705-16. doi: 10.1083/jcb.201503044. J Cell Biol. 2015. PMID: 26323688 Free PMC article.
SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.
Wei R, Xu LW, Liu J, Li Y, Zhang P, Shan B, Lu X, Qian L, Wu Z, Dong K, Zhu H, Pan L, Yuan J, Pan H. Wei R, et al. Among authors: pan l, pan h. Genes Dev. 2017 Jun 1;31(11):1162-1176. doi: 10.1101/gad.299776.117. Epub 2017 Jul 12. Genes Dev. 2017. PMID: 28701375 Free PMC article.
8,368 results