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Discovery of a cooperative mode of inhibiting RIPK1 kinase.
Meng H, Wu G, Zhao X, Wang A, Li D, Tong Y, Jin T, Cao Y, Shan B, Hu S, Li Y, Pan L, Tian X, Wu P, Peng C, Yuan J, Li G, Tan L, Wang Z, Li Y. Meng H, et al. Among authors: yuan j. Cell Discov. 2021 Jun 1;7(1):41. doi: 10.1038/s41421-021-00278-x. Cell Discov. 2021. PMID: 34075030 Free PMC article.
A novel necroptosis inhibitor-necrostatin-21 and its SAR study.
Wu Z, Li Y, Cai Y, Yuan J, Yuan C. Wu Z, et al. Among authors: yuan c, yuan j. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4903-6. doi: 10.1016/j.bmcl.2013.06.073. Epub 2013 Jul 3. Bioorg Med Chem Lett. 2013. PMID: 23886688
Chaperone-mediated autophagy degrades mutant p53.
Vakifahmetoglu-Norberg H, Kim M, Xia HG, Iwanicki MP, Ofengeim D, Coloff JL, Pan L, Ince TA, Kroemer G, Brugge JS, Yuan J. Vakifahmetoglu-Norberg H, et al. Among authors: yuan j. Genes Dev. 2013 Aug 1;27(15):1718-30. doi: 10.1101/gad.220897.113. Genes Dev. 2013. PMID: 23913924 Free PMC article.
Control of life-or-death decisions by RIP1 kinase.
Christofferson DE, Li Y, Yuan J. Christofferson DE, et al. Among authors: yuan j. Annu Rev Physiol. 2014;76:129-50. doi: 10.1146/annurev-physiol-021113-170259. Epub 2013 Sep 20. Annu Rev Physiol. 2014. PMID: 24079414 Review.
Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death.
Xia HG, Najafov A, Geng J, Galan-Acosta L, Han X, Guo Y, Shan B, Zhang Y, Norberg E, Zhang T, Pan L, Liu J, Coloff JL, Ofengeim D, Zhu H, Wu K, Cai Y, Yates JR, Zhu Z, Yuan J, Vakifahmetoglu-Norberg H. Xia HG, et al. Among authors: yuan j. J Cell Biol. 2015 Aug 31;210(5):705-16. doi: 10.1083/jcb.201503044. J Cell Biol. 2015. PMID: 26323688 Free PMC article.
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