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PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2).
Hawley E, Gehlhausen J, Karchugina S, Chow HY, Araiza-Olivera D, Radu M, Smith A, Burks C, Jiang L, Li X, Bessler W, Masters A, Edwards D, Burgin C, Jones D, Yates C, Clapp DW, Chernoff J, Park SJ. Hawley E, et al. Among authors: chernoff j. Hum Mol Genet. 2021 Aug 12;30(17):1607-1617. doi: 10.1093/hmg/ddab106. Hum Mol Genet. 2021. PMID: 34075397 Free PMC article.
NF2: the wizardry of merlin.
Xiao GH, Chernoff J, Testa JR. Xiao GH, et al. Among authors: chernoff j. Genes Chromosomes Cancer. 2003 Dec;38(4):389-99. doi: 10.1002/gcc.10282. Genes Chromosomes Cancer. 2003. PMID: 14566860 Review.
p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics.
Allen JD, Jaffer ZM, Park SJ, Burgin S, Hofmann C, Sells MA, Chen S, Derr-Yellin E, Michels EG, McDaniel A, Bessler WK, Ingram DA, Atkinson SJ, Travers JB, Chernoff J, Clapp DW. Allen JD, et al. Among authors: chernoff j. Blood. 2009 Mar 19;113(12):2695-705. doi: 10.1182/blood-2008-06-160861. Epub 2009 Jan 5. Blood. 2009. PMID: 19124833 Free PMC article.
The DeMSTification of mammalian Ste20 kinases.
Radu M, Chernoff J. Radu M, et al. Among authors: chernoff j. Curr Biol. 2009 May 26;19(10):R421-5. doi: 10.1016/j.cub.2009.04.022. Curr Biol. 2009. PMID: 19467213 Free article. Review.
An emerging role for p21-activated kinases (Paks) in viral infections.
Van den Broeke C, Radu M, Chernoff J, Favoreel HW. Van den Broeke C, et al. Among authors: chernoff j. Trends Cell Biol. 2010 Mar;20(3):160-9. doi: 10.1016/j.tcb.2009.12.005. Epub 2010 Jan 12. Trends Cell Biol. 2010. PMID: 20071173 Free PMC article. Review.
225 results