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Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling.
Zareie P, Szeto C, Farenc C, Gunasinghe SD, Kolawole EM, Nguyen A, Blyth C, Sng XYX, Li J, Jones CM, Fulcher AJ, Jacobs JR, Wei Q, Wojciech L, Petersen J, Gascoigne NRJ, Evavold BD, Gaus K, Gras S, Rossjohn J, La Gruta NL. Zareie P, et al. Among authors: gaus k. Science. 2021 Jun 4;372(6546):eabe9124. doi: 10.1126/science.abe9124. Science. 2021. PMID: 34083463
Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination.
Pageon SV, Tabarin T, Yamamoto Y, Ma Y, Nicovich PR, Bridgeman JS, Cohnen A, Benzing C, Gao Y, Crowther MD, Tungatt K, Dolton G, Sewell AK, Price DA, Acuto O, Parton RG, Gooding JJ, Rossy J, Rossjohn J, Gaus K. Pageon SV, et al. Among authors: gaus k. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5454-63. doi: 10.1073/pnas.1607436113. Epub 2016 Aug 29. Proc Natl Acad Sci U S A. 2016. PMID: 27573839 Free PMC article.
Biomechanics of T Cell Dysfunctions in Chronic Diseases.
Gunasinghe SD, Peres NG, Goyette J, Gaus K. Gunasinghe SD, et al. Among authors: gaus k. Front Immunol. 2021 Feb 25;12:600829. doi: 10.3389/fimmu.2021.600829. eCollection 2021. Front Immunol. 2021. PMID: 33717081 Free PMC article. Review.
A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells.
Lim HJ, Wubben JM, Garcia CP, Cruz-Gomez S, Deng J, Mak JYW, Hachani A, Anderson RJ, Painter GF, Goyette J, Amarasinghe SL, Ritchie ME, Roquilly A, Fairlie DP, Gaus K, Rossjohn J, Villadangos JA, McWilliam HEG. Lim HJ, et al. Among authors: gaus k. J Cell Biol. 2022 Dec 5;221(12):e202110125. doi: 10.1083/jcb.202110125. Epub 2022 Sep 21. J Cell Biol. 2022. PMID: 36129434 Free PMC article.
234 results