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Revealing the spatio-phenotypic patterning of cells in healthy and tumor tissues with mLSR-3D and STAPL-3D.
van Ineveld RL, Kleinnijenhuis M, Alieva M, de Blank S, Barrera Roman M, van Vliet EJ, Martínez Mir C, Johnson HR, Bos FL, Heukers R, Chuva de Sousa Lopes SM, Drost J, Dekkers JF, Wehrens EJ, Rios AC. van Ineveld RL, et al. Among authors: drost j. Nat Biotechnol. 2021 Oct;39(10):1239-1245. doi: 10.1038/s41587-021-00926-3. Epub 2021 Jun 3. Nat Biotechnol. 2021. PMID: 34083793 Free PMC article.
Tubuloids derived from human adult kidney and urine for personalized disease modeling.
Schutgens F, Rookmaaker MB, Margaritis T, Rios A, Ammerlaan C, Jansen J, Gijzen L, Vormann M, Vonk A, Viveen M, Yengej FY, Derakhshan S, de Winter-de Groot KM, Artegiani B, van Boxtel R, Cuppen E, Hendrickx APA, van den Heuvel-Eibrink MM, Heitzer E, Lanz H, Beekman J, Murk JL, Masereeuw R, Holstege F, Drost J, Verhaar MC, Clevers H. Schutgens F, et al. Among authors: drost j. Nat Biotechnol. 2019 Mar;37(3):303-313. doi: 10.1038/s41587-019-0048-8. Epub 2019 Mar 4. Nat Biotechnol. 2019. PMID: 30833775
An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity.
Calandrini C, Schutgens F, Oka R, Margaritis T, Candelli T, Mathijsen L, Ammerlaan C, van Ineveld RL, Derakhshan S, de Haan S, Dolman E, Lijnzaad P, Custers L, Begthel H, Kerstens HHD, Visser LL, Rookmaaker M, Verhaar M, Tytgat GAM, Kemmeren P, de Krijger RR, Al-Saadi R, Pritchard-Jones K, Kool M, Rios AC, van den Heuvel-Eibrink MM, Molenaar JJ, van Boxtel R, Holstege FCP, Clevers H, Drost J. Calandrini C, et al. Among authors: drost j. Nat Commun. 2020 Mar 11;11(1):1310. doi: 10.1038/s41467-020-15155-6. Nat Commun. 2020. PMID: 32161258 Free PMC article.
LGR6 marks nephron progenitor cells.
van Ineveld RL, Margaritis T, Kooiman BAP, Groenveld F, Ariese HCR, Lijnzaad P, Johnson HR, Korving J, Wehrens EJ, Holstege F, van Rheenen J, Drost J, Rios AC, Bos FL. van Ineveld RL, et al. Among authors: drost j. Dev Dyn. 2021 Nov;250(11):1568-1583. doi: 10.1002/dvdy.346. Epub 2021 May 6. Dev Dyn. 2021. PMID: 33848015 Free PMC article.
The Virtual Child.
Gilbertson RJ, Behjati S, Böttcher AL, Bronner ME, Burridge M, Clausing H, Clifford H, Danaher T, Donovan LK, Drost J, Eggermont AMM, Emerson C, Flores MG, Hamerlik P, Jabado N, Jones A, Kaessmann H, Kleinman CL, Kool M, Kutscher LM, Lindberg G, Linnane E, Marioni JC, Maris JM, Monje M, Macaskill A, Niederer S, Northcott PA, Peeters E, Plieger-van Solkema W, Preußner L, Rios AC, Rippe K, Sandford P, Sgourakis NG, Shlien A, Smith P, Straathof K, Sullivan PJ, Suvà ML, Taylor MD, Thompson E, Vento-Tormo R, Wainwright BJ, Wechsler-Reya RJ, Westermann F, Winslade S, Al-Lazikani B, Pfister SM. Gilbertson RJ, et al. Among authors: drost j. Cancer Discov. 2024 Apr 4;14(4):663-668. doi: 10.1158/2159-8290.CD-23-1500. Cancer Discov. 2024. PMID: 38571421
Organoids in cancer research.
Drost J, Clevers H. Drost J, et al. Nat Rev Cancer. 2018 Jul;18(7):407-418. doi: 10.1038/s41568-018-0007-6. Nat Rev Cancer. 2018. PMID: 29692415 Review.
Organoid models of childhood kidney tumours.
Ooms AHAG, Calandrini C, de Krijger RR, Drost J. Ooms AHAG, et al. Among authors: drost j. Nat Rev Urol. 2020 Jun;17(6):311-313. doi: 10.1038/s41585-020-0315-y. Nat Rev Urol. 2020. PMID: 32242130 No abstract available.
Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours.
Custers L, Khabirova E, Coorens THH, Oliver TRW, Calandrini C, Young MD, Vieira Braga FA, Ellis P, Mamanova L, Segers H, Maat A, Kool M, Hoving EW, van den Heuvel-Eibrink MM, Nicholson J, Straathof K, Hook L, de Krijger RR, Trayers C, Allinson K, Behjati S, Drost J. Custers L, et al. Among authors: drost j. Nat Commun. 2021 Mar 3;12(1):1407. doi: 10.1038/s41467-021-21675-6. Nat Commun. 2021. PMID: 33658498 Free PMC article.
149 results