Wu T - Search Results

1

Synthesis, SAR study, and bioactivity evaluation of a series of Quinoline-Indole-Schiff base derivatives: Compound 10E as a new Nur77 exporter and autophagic death inducer.

Li B, Yao J, He F, Liu J, Lin Z, Liu S, Wang W, Wu T, Huang J, Chen K, Fang M, Chen J, Zeng JZ. Li B, et al. Among authors: wu t. Bioorg Chem. 2021 Aug;113:105008. doi: 10.1016/j.bioorg.2021.105008. Epub 2021 May 23. Bioorg Chem. 2021. PMID: 34089944

2

Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.

Li B, Zhu F, He F, Huang Q, Liu X, Wu T, Zhao T, Qiu Y, Wu Z, Xue Y, Fang M. Li B, et al. Among authors: wu t, wu z. Bioorg Chem. 2020 Mar;96:103592. doi: 10.1016/j.bioorg.2020.103592. Epub 2020 Jan 20. Bioorg Chem. 2020. PMID: 32044517

3

Synthesis and biological evaluation of (3/4-(pyrimidin-2-ylamino)benzoyl)-based hydrazine-1-carboxamide/carbothioamide derivatives as novel RXRα antagonists.

Qin J, Liu J, Wu C, Xu J, Tang B, Guo K, Chen X, Liu W, Wu T, Zhou H, Fang M, Wu Z. Qin J, et al. Among authors: wu t, wu c, wu z. J Enzyme Inhib Med Chem. 2020 Dec;35(1):880-896. doi: 10.1080/14756366.2020.1740692. J Enzyme Inhib Med Chem. 2020. PMID: 32223461 Free PMC article.

4

Design, synthesis and biological evaluation of methylenehydrazine-1-carboxamide derivatives with (5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole scaffold: Novel potential CDK9 inhibitors.

Hu H, Wu J, Ao M, Zhou X, Li B, Cui Z, Wu T, Wang L, Xue Y, Wu Z, Fang M. Hu H, et al. Among authors: wu t, wu j, wu z. Bioorg Chem. 2020 Sep;102:104064. doi: 10.1016/j.bioorg.2020.104064. Epub 2020 Jun 30. Bioorg Chem. 2020. PMID: 32653610

5

Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma.

Li B, Huang J, Liu J, He F, Wen F, Yang C, Wang W, Wu T, Zhao T, Yao J, Liu S, Qiu Y, Fang M, Zeng J, Wu Z. Li B, et al. Among authors: wu t, wu z. Bioorg Chem. 2022 Apr;121:105651. doi: 10.1016/j.bioorg.2022.105651. Epub 2022 Feb 12. Bioorg Chem. 2022. PMID: 35182885

6

AI-Aided Design of Novel Targeted Covalent Inhibitors against SARS-CoV-2.

Tang B, He F, Liu D, He F, Wu T, Fang M, Niu Z, Wu Z, Xu D. Tang B, et al. Among authors: wu t, wu z. Biomolecules. 2022 May 25;12(6):746. doi: 10.3390/biom12060746. Biomolecules. 2022. PMID: 35740872 Free PMC article.

7

Novel 2, 5-diketopiperazine derivatives as potent selective histone deacetylase 6 inhibitors: Rational design, synthesis and antiproliferative activity.

Chen X, Chen X, Steimbach RR, Wu T, Li H, Dan W, Shi P, Cao C, Li D, Miller AK, Qiu Z, Gao J, Zhu Y. Chen X, et al. Among authors: wu t. Eur J Med Chem. 2020 Feb 1;187:111950. doi: 10.1016/j.ejmech.2019.111950. Epub 2019 Dec 6. Eur J Med Chem. 2020. PMID: 31865013

8

Pan-coronavirus fusion inhibitors possess potent inhibitory activity against HIV-1, HIV-2, and simian immunodeficiency virus.

Yu D, Zhu Y, Yan H, Wu T, Chong H, He Y. Yu D, et al. Among authors: wu t. Emerg Microbes Infect. 2021 Dec;10(1):810-821. doi: 10.1080/22221751.2021.1917309. Emerg Microbes Infect. 2021. PMID: 33847245 Free PMC article.

9

Structure-based design and characterization of novel fusion-inhibitory lipopeptides against SARS-CoV-2 and emerging variants.

Yu D, Zhu Y, Jiao T, Wu T, Xiao X, Qin B, Chong H, Lei X, Ren L, Cui S, Wang J, He Y. Yu D, et al. Among authors: wu t. Emerg Microbes Infect. 2021 Dec;10(1):1227-1240. doi: 10.1080/22221751.2021.1937329. Emerg Microbes Infect. 2021. PMID: 34057039 Free PMC article.

10

SARS-CoV-2-derived fusion inhibitor lipopeptides exhibit highly potent and broad-spectrum activity against divergent human coronaviruses.

Zhu Y, Yu D, Hu Y, Wu T, Chong H, He Y. Zhu Y, et al. Among authors: wu t. Signal Transduct Target Ther. 2021 Aug 3;6(1):294. doi: 10.1038/s41392-021-00698-x. Signal Transduct Target Ther. 2021. PMID: 34344868 Free PMC article. No abstract available.

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