Ezell EL - Search Results

1

Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy.

Sagar S, Singh S, Mallareddy JR, Sonawane YA, Napoleon JV, Rana S, Contreras JI, Rajesh C, Ezell EL, Kizhake S, Garrison JC, Radhakrishnan P, Natarajan A. Sagar S, et al. Among authors: ezell el. Eur J Med Chem. 2021 Oct 15;222:113579. doi: 10.1016/j.ejmech.2021.113579. Epub 2021 May 30. Eur J Med Chem. 2021. PMID: 34098465 Free PMC article.

2

Aminopyrazole based CDK9 PROTAC sensitizes pancreatic cancer cells to venetoclax.

King HM, Rana S, Kubica SP, Mallareddy JR, Kizhake S, Ezell EL, Zahid M, Naldrett MJ, Alvarez S, Law HC, Woods NT, Natarajan A. King HM, et al. Among authors: ezell el. Bioorg Med Chem Lett. 2021 Jul 1;43:128061. doi: 10.1016/j.bmcl.2021.128061. Epub 2021 Apr 23. Bioorg Med Chem Lett. 2021. PMID: 33895280 Free PMC article.

3

Structure-Activity Relationship Studies with Tetrahydroquinoline Analogs as EPAC Inhibitors.

Sonawane YA, Zhu Y, Garrison JC, Ezell EL, Zahid M, Cheng X, Natarajan A. Sonawane YA, et al. Among authors: ezell el. ACS Med Chem Lett. 2017 Oct 2;8(11):1183-1187. doi: 10.1021/acsmedchemlett.7b00358. eCollection 2017 Nov 9. ACS Med Chem Lett. 2017. PMID: 29375750 Free PMC article.

4

Tricyclic Imidazolidin-4-ones by Witkop Oxidation of Tetrahydro-β-carbolines.

Leas DA, Dong Y, Garrison JC, Wang X, Ezell EL, Stack DE, Vennerstrom JL. Leas DA, et al. Among authors: ezell el. J Org Chem. 2020 Feb 21;85(4):2846-2853. doi: 10.1021/acs.joc.9b03402. Epub 2020 Jan 10. J Org Chem. 2020. PMID: 31904963 Free PMC article.

5

Formation of 2-Imino Benzo[e]-1,3-oxazin-4-ones from Reactions of Salicylic Acids and Anilines with HATU: Mechanistic and Synthetic Studies.

Leas DA, Wu J, Ezell EL, Garrison JC, Vennerstrom JL, Dong Y. Leas DA, et al. Among authors: ezell el. ACS Omega. 2018 Jan 31;3(1):781-787. doi: 10.1021/acsomega.7b01824. Epub 2018 Jan 22. ACS Omega. 2018. PMID: 29399653 Free PMC article.

6

N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα).

Sabbah DA, Simms NA, Wang W, Dong Y, Ezell EL, Brattain MG, Vennerstrom JL, Zhong HA. Sabbah DA, et al. Among authors: ezell el. Bioorg Med Chem. 2012 Dec 15;20(24):7175-83. doi: 10.1016/j.bmc.2012.09.059. Epub 2012 Oct 12. Bioorg Med Chem. 2012. PMID: 23121722

7

CCDI: a new ligand that modulates mammalian type 1 ryanodine receptor (RyR1).

Tian C, Shao CH, Padanilam C, Ezell E, Singh J, Kutty S, Bidasee KR. Tian C, et al. Br J Pharmacol. 2014 Sep;171(17):4097-111. doi: 10.1111/bph.12764. Epub 2014 Jul 2. Br J Pharmacol. 2014. PMID: 24819467 Free PMC article.

8

Lipophilic pyrylium salts in the synthesis of efficient pyridinium-based cationic lipids, gemini surfactants, and lipophilic oligomers for gene delivery.

Ilies MA, Seitz WA, Johnson BH, Ezell EL, Miller AL, Thompson EB, Balaban AT. Ilies MA, et al. Among authors: ezell el. J Med Chem. 2006 Jun 29;49(13):3872-87. doi: 10.1021/jm0601755. J Med Chem. 2006. PMID: 16789743

9

Tetrasubstituted pyrazinones derived from the reaction of praziquantel with N-bromosuccinimide.

Zhao Q, Wang C, Ezell EL, Dong Y, Vennerstrom JL. Zhao Q, et al. Among authors: ezell el. Tetrahedron Lett. 2014 Aug 6;55(32):4463-4465. doi: 10.1016/j.tetlet.2014.06.083. Tetrahedron Lett. 2014. PMID: 25125709 Free PMC article.

10

Synthesis of 2-Azaadamantan-6-one: A Missing Isomer.

Wu J, Leas DA, Dong Y, Wang X, Ezell EL, Stack DE, Vennerstrom JL. Wu J, et al. Among authors: ezell el. ACS Omega. 2018 Sep 30;3(9):11362-11367. doi: 10.1021/acsomega.8b01819. Epub 2018 Sep 18. ACS Omega. 2018. PMID: 30288462 Free PMC article.

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