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Exploring the Role of RGD-Recognizing Integrins in Cancer.
Nieberler M, Reuning U, Reichart F, Notni J, Wester HJ, Schwaiger M, Weinmüller M, Räder A, Steiger K, Kessler H. Nieberler M, et al. Among authors: kessler h. Cancers (Basel). 2017 Sep 4;9(9):116. doi: 10.3390/cancers9090116. Cancers (Basel). 2017. PMID: 28869579 Free PMC article. Review.
Improving oral bioavailability of cyclic peptides by N-methylation.
Räder AFB, Reichart F, Weinmüller M, Kessler H. Räder AFB, et al. Among authors: kessler h. Bioorg Med Chem. 2018 Jun 1;26(10):2766-2773. doi: 10.1016/j.bmc.2017.08.031. Epub 2017 Aug 31. Bioorg Med Chem. 2018. PMID: 28886995 Free article. Review.
Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvβ3.
Weinmüller M, Rechenmacher F, Kiran Marelli U, Reichart F, Kapp TG, Räder AFB, Di Leva FS, Marinelli L, Novellino E, Muñoz-Félix JM, Hodivala-Dilke K, Schumacher A, Fanous J, Gilon C, Hoffman A, Kessler H. Weinmüller M, et al. Among authors: kessler h. Angew Chem Int Ed Engl. 2017 Dec 18;56(51):16405-16409. doi: 10.1002/anie.201709709. Epub 2017 Nov 23. Angew Chem Int Ed Engl. 2017. PMID: 29072809
Enhancing Oral Bioavailability of Cyclic RGD Hexa-peptides by the Lipophilic Prodrug Charge Masking Approach: Redirection of Peptide Intestinal Permeability from a Paracellular to Transcellular Pathway.
Schumacher-Klinger A, Fanous J, Merzbach S, Weinmüller M, Reichart F, Räder AFB, Gitlin-Domagalska A, Gilon C, Kessler H, Hoffman A. Schumacher-Klinger A, et al. Among authors: kessler h. Mol Pharm. 2018 Aug 6;15(8):3468-3477. doi: 10.1021/acs.molpharmaceut.8b00466. Epub 2018 Jul 25. Mol Pharm. 2018. PMID: 29976060
Orally Active Peptides: Is There a Magic Bullet?
Räder AFB, Weinmüller M, Reichart F, Schumacher-Klinger A, Merzbach S, Gilon C, Hoffman A, Kessler H. Räder AFB, et al. Among authors: kessler h. Angew Chem Int Ed Engl. 2018 Oct 26;57(44):14414-14438. doi: 10.1002/anie.201807298. Epub 2018 Oct 3. Angew Chem Int Ed Engl. 2018. PMID: 30144240 Review.
Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide.
Reichart F, Maltsev OV, Kapp TG, Räder AFB, Weinmüller M, Marelli UK, Notni J, Wurzer A, Beck R, Wester HJ, Steiger K, Di Maro S, Di Leva FS, Marinelli L, Nieberler M, Reuning U, Schwaiger M, Kessler H. Reichart F, et al. Among authors: kessler h. J Med Chem. 2019 Feb 28;62(4):2024-2037. doi: 10.1021/acs.jmedchem.8b01588. Epub 2019 Feb 6. J Med Chem. 2019. PMID: 30657681
1,224 results