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Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission.
Chang XL, Webb GM, Wu HL, Greene JM, Abdulhaqq S, Bateman KB, Reed JS, Pessoa C, Weber WC, Maier N, Chew GM, Gilbride RM, Gao L, Agnor R, Giobbi T, Torgerson J, Siess D, Burnett N, Fischer M, Shiel O, Moats C, Patterson B, Dhody K, Kelly S, Pourhassan N, Magnani DM, Smedley J, Bimber BN, Haigwood NL, Hansen SG, Brown TR, Ndhlovu LC, Sacha JB. Chang XL, et al. Among authors: pessoa c. Nat Commun. 2021 Jun 7;12(1):3343. doi: 10.1038/s41467-021-23697-6. Nat Commun. 2021. PMID: 34099693 Free PMC article.
CCR5 Receptor Occupancy Analysis Reveals Increased Peripheral Blood CCR5+CD4+ T Cells Following Treatment With the Anti-CCR5 Antibody Leronlimab.
Chang XL, Wu HL, Webb GM, Tiwary M, Hughes C, Reed JS, Hwang J, Waytashek C, Boyle C, Pessoa C, Sylwester AW, Morrow D, Belica K, Fischer M, Kelly S, Pourhassan N, Bochart RM, Smedley J, Recknor CP, Hansen SG, Sacha JB. Chang XL, et al. Among authors: pessoa c. Front Immunol. 2021 Nov 19;12:794638. doi: 10.3389/fimmu.2021.794638. eCollection 2021. Front Immunol. 2021. PMID: 34868084 Free PMC article. Clinical Trial.
Suppression of human and simian immunodeficiency virus replication with the CCR5-specific antibody Leronlimab in two species.
Chang XL, Reed JS, Webb GM, Wu HL, Le J, Bateman KB, Greene JM, Pessoa C, Waytashek C, Weber WC, Hwang J, Fischer M, Moats C, Shiel O, Bochart RM, Crank H, Siess D, Giobbi T, Torgerson J, Agnor R, Gao L, Dhody K, Lalezari JP, Bandar IS, Carnate AM, Pang AS, Corley MJ, Kelly S, Pourhassan N, Smedley J, Bimber BN, Hansen SG, Ndhlovu LC, Sacha JB. Chang XL, et al. Among authors: pessoa c. PLoS Pathog. 2022 Mar 31;18(3):e1010396. doi: 10.1371/journal.ppat.1010396. eCollection 2022 Mar. PLoS Pathog. 2022. PMID: 35358290 Free PMC article.
Immune restoration by TIGIT blockade is insufficient to control chronic SIV infection.
Webb GM, Pessoa CT, McCullen AJ, Hwang JM, Humkey MC, Thormin-Odum R, Kukula KA, Smedley J, Fischer M, Sciurba J, Bochart RM, Shriver-Munsch C, Ndhlovu LC, Sacha JB. Webb GM, et al. Among authors: pessoa ct. J Virol. 2024 Jun 13;98(6):e0027324. doi: 10.1128/jvi.00273-24. Epub 2024 May 22. J Virol. 2024. PMID: 38775481 Free PMC article.
Effect of metabolic status on response to SIV infection and antiretroviral therapy in nonhuman primates.
Webb GM, Sauter KA, Takahashi D, Kirigiti M, Bader L, Lindsley SR, Blomenkamp H, Zaro C, Shallman M, McGuire C, Hofmeister H, Avila U, Pessoa C, Hwang JM, McCullen A, Humkey M, Reed J, Gao L, Winchester L, Fletcher CV, Varlamov O, Brown TT, Sacha JB, Kievit P, Roberts CT. Webb GM, et al. Among authors: pessoa c. JCI Insight. 2024 Aug 8;9(18):e181968. doi: 10.1172/jci.insight.181968. JCI Insight. 2024. PMID: 39115937 Free PMC article.
Sodium hyaluronate microcapsules to promote antitumor selectivity of anacardic acid.
Rosa MEP, Rebouças LM, Marques SPD, Silva LMR, Cunha FET, Costa PMS, de Assis DA, Silveira KB, Muniz CR, Trevisan MTS, Pessoa C, Ricardo NMPS. Rosa MEP, et al. Among authors: pessoa c. Int J Biol Macromol. 2025 Jan 10;296:139616. doi: 10.1016/j.ijbiomac.2025.139616. Online ahead of print. Int J Biol Macromol. 2025. PMID: 39800027
In Silico Study of the Anti-MYC Potential of Lanostane-Type Triterpenes.
Oliveira JAC, Negreiro JM, Nunes FM, Barbosa FG, Mafezoli J, Mattos MC, Fernandes MCR, Pessoa C, Furtado CLM, Zanatta G, Oliveira MCF. Oliveira JAC, et al. Among authors: pessoa c. ACS Omega. 2024 Dec 12;9(51):50844-50858. doi: 10.1021/acsomega.4c10201. eCollection 2024 Dec 24. ACS Omega. 2024. PMID: 39741863 Free PMC article.
Synthesis and characterization of new quaternized galactomannan derivatives with antibacterial activity.
do Nascimento EPA, de Oliveira Silva Ribeiro F, Rodrigues RRL, da Franca Rodrigues KA, de Araujo Sousa PS, Rocha JA, de Cássia Evangelista de Oliveira F, Pessoa C, de Lima LRM, do N Ferreira CR, de Paula RCM, Feitosa JPA, da Silva Filho EC, de Araujo-Nobre AR, da Silva DA. do Nascimento EPA, et al. Among authors: pessoa c. Int J Biol Macromol. 2024 Dec;283(Pt 2):137693. doi: 10.1016/j.ijbiomac.2024.137693. Epub 2024 Nov 15. Int J Biol Macromol. 2024. PMID: 39551303
365 results