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A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl.
Triller G, Vlachou EP, Hashemi H, van Straaten M, Zeelen JP, Kelemen Y, Baehr C, Marker CL, Ruf S, Svirina A, Chandra M, Urban K, Gkeka A, Kruse S, Baumann A, Miller AK, Bartel M, Pravetoni M, Stebbins CE, Papavasiliou FN, Verdi JP. Triller G, et al. Among authors: chandra m. Cell Rep. 2023 Feb 28;42(2):112049. doi: 10.1016/j.celrep.2023.112049. Epub 2023 Jan 30. Cell Rep. 2023. PMID: 36719797 Free PMC article.
Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome.
Chandra M, Đaković S, Foti K, Zeelen JP, van Straaten M, Aresta-Branco F, Tihon E, Lübbehusen N, Ruppert T, Glover L, Papavasiliou FN, Stebbins CE. Chandra M, et al. PLoS Negl Trop Dis. 2023 Feb 13;17(2):e0011093. doi: 10.1371/journal.pntd.0011093. eCollection 2023 Feb. PLoS Negl Trop Dis. 2023. PMID: 36780870 Free PMC article.
A structural classification of the variant surface glycoproteins of the African trypanosome.
Đaković S, Zeelen JP, Gkeka A, Chandra M, van Straaten M, Foti K, Zhong J, Vlachou EP, Aresta-Branco F, Verdi JP, Papavasiliou FN, Stebbins CE. Đaković S, et al. Among authors: chandra m. PLoS Negl Trop Dis. 2023 Sep 1;17(9):e0011621. doi: 10.1371/journal.pntd.0011621. eCollection 2023 Sep. PLoS Negl Trop Dis. 2023. PMID: 37656766 Free PMC article.
The fentanyl-specific antibody FenAb024 can shield against carfentanil effects.
Urban K, Gkeka A, Chandra M, Greiner D, Pollich S, Ruf S, Kelemen Y, Sundermann T, Pravetoni M, Baehr C, Stebbins CE, Papavasiliou FN, Verdi JP. Urban K, et al. Among authors: chandra m. Toxicol Lett. 2024 May 15;396:1-10. doi: 10.1016/j.toxlet.2024.03.008. Epub 2024 Apr 6. Toxicol Lett. 2024. PMID: 38588756 Free article.
Targeting the lung tumor microenvironment by phytochemicals and their nanoformulations.
Obaidur Rab S, Altalbawy FMA, Chandra M, Ariffin IA, Kaur P, Rathore G, Rizaev J, Aloraibi F, Najeeb MA, Abdulhussain MA, Zwamel AH. Obaidur Rab S, et al. Among authors: chandra m. Pathol Res Pract. 2024 Dec;264:155679. doi: 10.1016/j.prp.2024.155679. Epub 2024 Oct 28. Pathol Res Pract. 2024. PMID: 39500198 Review.
800 results