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Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials.
Grundman M, Petersen RC, Ferris SH, Thomas RG, Aisen PS, Bennett DA, Foster NL, Jack CR Jr, Galasko DR, Doody R, Kaye J, Sano M, Mohs R, Gauthier S, Kim HT, Jin S, Schultz AN, Schafer K, Mulnard R, van Dyck CH, Mintzer J, Zamrini EY, Cahn-Weiner D, Thal LJ; Alzheimer's Disease Cooperative Study. Grundman M, et al. Among authors: aisen ps. Arch Neurol. 2004 Jan;61(1):59-66. doi: 10.1001/archneur.61.1.59. Arch Neurol. 2004. PMID: 14732621 Clinical Trial.
Alzhemed: a potential treatment for Alzheimer's disease.
Aisen PS, Gauthier S, Vellas B, Briand R, Saumier D, Laurin J, Garceau D. Aisen PS, et al. Curr Alzheimer Res. 2007 Sep;4(4):473-8. doi: 10.2174/156720507781788882. Curr Alzheimer Res. 2007. PMID: 17908052 Review.
A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium.
Khachaturian ZS, Petersen RC, Gauthier S, Buckholtz N, Corey-Bloom JP, Evans B, Fillit H, Foster N, Greenberg B, Grundman M, Sano M, Simpkins J, Schneider LS, Weiner MW, Galasko D, Hyman B, Kuller L, Schenk D, Snyder S, Thomas RG, Tuszynski MH, Vellas B, Wurtman RJ, Snyder PJ, Frank RA, Albert M, Doody R, Ferris S, Kaye J, Koo E, Morrison-Bogorad M, Reisberg B, Salmon DP, Gilman S, Mohs R, Aisen PS, Breitner JC, Cummings JL, Kawas C, Phelps C, Poirier J, Sabbagh M, Touchon J, Khachaturian AS, Bain LJ. Khachaturian ZS, et al. Among authors: aisen ps. Alzheimers Dement. 2008 May;4(3):156-63. doi: 10.1016/j.jalz.2008.03.005. Alzheimers Dement. 2008. PMID: 18631960 Free PMC article. No abstract available.
Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study.
Doody RS, Gavrilova SI, Sano M, Thomas RG, Aisen PS, Bachurin SO, Seely L, Hung D; dimebon investigators. Doody RS, et al. Among authors: aisen ps. Lancet. 2008 Jul 19;372(9634):207-15. doi: 10.1016/S0140-6736(08)61074-0. Lancet. 2008. PMID: 18640457 Clinical Trial.
Methodological issues in primary prevention trials for neurodegenerative dementia.
Andrieu S, Coley N, Aisen P, Carrillo MC, DeKosky S, Durga J, Fillit H, Frisoni GB, Froelich L, Gauthier S, Jones R, Jönsson L, Khachaturian Z, Morris JC, Orgogozo JM, Ousset PJ, Robert P, Salmon E, Sampaio C, Verhey F, Wilcock G, Vellas B. Andrieu S, et al. J Alzheimers Dis. 2009;16(2):235-70. doi: 10.3233/JAD-2009-0971. J Alzheimers Dis. 2009. PMID: 19221415 Review.
Lessons learned in the use of volumetric MRI in therapeutic trials in Alzheimer's disease: the ALZHEMED (Tramiprosate) experience.
Saumier D, Aisen PS, Gauthier S, Vellas B, Ferris SH, Duong A, Suhy J, Oh J, Lau W, Garceau D, Haine D, Sampalis J. Saumier D, et al. Among authors: aisen ps. J Nutr Health Aging. 2009 Apr;13(4):370-2. doi: 10.1007/s12603-009-0047-4. J Nutr Health Aging. 2009. PMID: 19300884 Free article. Clinical Trial. No abstract available.
A roadmap for the prevention of dementia II: Leon Thal Symposium 2008.
Khachaturian ZS, Snyder PJ, Doody R, Aisen P, Comer M, Dwyer J, Frank RA, Holzapfel A, Khachaturian AS, Korczyn AD, Roses A, Simpkins JW, Schneider LS, Albert MS, Egge R, Deves A, Ferris S, Greenberg BD, Johnson C, Kukull WA, Poirier J, Schenk D, Thies W, Gauthier S, Gilman S, Bernick C, Cummings JL, Fillit H, Grundman M, Kaye J, Mucke L, Reisberg B, Sano M, Pickeral O, Petersen RC, Mohs RC, Carrillo M, Corey-Bloom JP, Foster NL, Jacobsen S, Lee V, Potter WZ, Sabbagh MN, Salmon D, Trojanowski JQ, Wexler N, Bain LJ. Khachaturian ZS, et al. Alzheimers Dement. 2009 Mar;5(2):85-92. doi: 10.1016/j.jalz.2009.01.021. Alzheimers Dement. 2009. PMID: 19328434 Free PMC article.
661 results