Adams JJ - Search Results

1

A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy.

Chidiac R, Abedin M, Macleod G, Yang A, Thibeault PE, Blazer LL, Adams JJ, Zhang L, Roehrich H, Jo HN, Seshagiri S, Sidhu SS, Junge HJ, Angers S. Chidiac R, et al. Among authors: adams jj. EMBO Mol Med. 2021 Jul 7;13(7):e13977. doi: 10.15252/emmm.202113977. Epub 2021 Jun 9. EMBO Mol Med. 2021. PMID: 34105895 Free PMC article.

2

CDR-H3 diversity is not required for antigen recognition by synthetic antibodies.

Persson H, Ye W, Wernimont A, Adams JJ, Koide A, Koide S, Lam R, Sidhu SS. Persson H, et al. Among authors: adams jj. J Mol Biol. 2013 Feb 22;425(4):803-11. doi: 10.1016/j.jmb.2012.11.037. Epub 2012 Dec 3. J Mol Biol. 2013. PMID: 23219464 Free PMC article.

3

Recombinant genetic libraries and human monoclonal antibodies.

Adams JJ, Nelson B, Sidhu SS. Adams JJ, et al. Methods Mol Biol. 2014;1060:149-70. doi: 10.1007/978-1-62703-586-6_9. Methods Mol Biol. 2014. PMID: 24037841

4

Synthetic antibody technologies.

Adams JJ, Sidhu SS. Adams JJ, et al. Curr Opin Struct Biol. 2014 Feb;24:1-9. doi: 10.1016/j.sbi.2013.11.003. Epub 2013 Dec 4. Curr Opin Struct Biol. 2014. PMID: 24721448 Review.

5

Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.

Adams JJ, Narayanan S, Birnbaum ME, Sidhu SS, Blevins SJ, Gee MH, Sibener LV, Baker BM, Kranz DM, Garcia KC. Adams JJ, et al. Nat Immunol. 2016 Jan;17(1):87-94. doi: 10.1038/ni.3310. Epub 2015 Nov 2. Nat Immunol. 2016. PMID: 26523866 Free PMC article.

6

A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo.

Uppalapati M, Lee DJ, Mandal K, Li H, Miranda LP, Lowitz J, Kenney J, Adams JJ, Ault-Riché D, Kent SB, Sidhu SS. Uppalapati M, et al. Among authors: adams jj. ACS Chem Biol. 2016 Apr 15;11(4):1058-65. doi: 10.1021/acschembio.5b01006. Epub 2016 Feb 3. ACS Chem Biol. 2016. PMID: 26745345

7

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.

Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S. Steinhart Z, et al. Nat Med. 2017 Jan;23(1):60-68. doi: 10.1038/nm.4219. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869803

8

A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models.

Ling B, Watt K, Banerjee S, Newsted D, Truesdell P, Adams J, Sidhu SS, Craig AWB. Ling B, et al. Oncotarget. 2017 May 9;8(35):58372-58385. doi: 10.18632/oncotarget.17702. eCollection 2017 Aug 29. Oncotarget. 2017. PMID: 28938563 Free PMC article.

9

Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.

Pollock SB, Hu A, Mou Y, Martinko AJ, Julien O, Hornsby M, Ploder L, Adams JJ, Geng H, Müschen M, Sidhu SS, Moffat J, Wells JA. Pollock SB, et al. Among authors: adams jj. Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2836-2841. doi: 10.1073/pnas.1721899115. Epub 2018 Feb 23. Proc Natl Acad Sci U S A. 2018. PMID: 29476010 Free PMC article.

10

Structure-Guided Combinatorial Engineering Facilitates Affinity and Specificity Optimization of Anti-CD81 Antibodies.

Nelson B, Adams J, Kuglstatter A, Li Z, Harris SF, Liu Y, Bohini S, Ma H, Klumpp K, Gao J, Sidhu SS. Nelson B, et al. J Mol Biol. 2018 Jul 6;430(14):2139-2152. doi: 10.1016/j.jmb.2018.05.018. Epub 2018 May 17. J Mol Biol. 2018. PMID: 29778602

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