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A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance.
Warshauer JT, Belk JA, Chan AY, Wang J, Gupta AR, Shi Q, Skartsis N, Peng Y, Phipps JD, Acenas D, Smith JA, Tamaki SJ, Tang Q, Gardner JM, Satpathy AT, Anderson MS. Warshauer JT, et al. Among authors: gardner jm. J Exp Med. 2021 Aug 2;218(8):e20210759. doi: 10.1084/jem.20210759. Epub 2021 Jun 11. J Exp Med. 2021. PMID: 34115115 Free PMC article.
Deletional tolerance mediated by extrathymic Aire-expressing cells.
Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, Johannes KP, Su MA, Chang HY, Krummel MF, Anderson MS. Gardner JM, et al. Science. 2008 Aug 8;321(5890):843-7. doi: 10.1126/science.1159407. Science. 2008. PMID: 18687966 Free PMC article.
The sickness unto Deaf.
Gardner JM, Anderson MS. Gardner JM, et al. Nat Immunol. 2009 Sep;10(9):934-6. doi: 10.1038/ni0909-934. Nat Immunol. 2009. PMID: 19692991 Free PMC article.
AIRE in the thymus and beyond.
Gardner JM, Fletcher AL, Anderson MS, Turley SJ. Gardner JM, et al. Curr Opin Immunol. 2009 Dec;21(6):582-9. doi: 10.1016/j.coi.2009.08.007. Epub 2009 Oct 14. Curr Opin Immunol. 2009. PMID: 19833494 Free PMC article. Review.
Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo.
Yadav M, Louvet C, Davini D, Gardner JM, Martinez-Llordella M, Bailey-Bucktrout S, Anthony BA, Sverdrup FM, Head R, Kuster DJ, Ruminski P, Weiss D, Von Schack D, Bluestone JA. Yadav M, et al. Among authors: gardner jm. J Exp Med. 2012 Sep 24;209(10):1713-22, S1-19. doi: 10.1084/jem.20120822. Epub 2012 Sep 10. J Exp Med. 2012. PMID: 22966003 Free PMC article.
Extrathymic Aire-expressing cells support maternal-fetal tolerance.
Gillis-Buck E, Miller H, Sirota M, Sanders SJ, Ntranos V, Anderson MS, Gardner JM, MacKenzie TC. Gillis-Buck E, et al. Among authors: gardner jm. Sci Immunol. 2021 Jul 16;6(61):eabf1968. doi: 10.1126/sciimmunol.abf1968. Sci Immunol. 2021. PMID: 34272228 Free PMC article.
411 results