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A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance.
Warshauer JT, Belk JA, Chan AY, Wang J, Gupta AR, Shi Q, Skartsis N, Peng Y, Phipps JD, Acenas D, Smith JA, Tamaki SJ, Tang Q, Gardner JM, Satpathy AT, Anderson MS. Warshauer JT, et al. Among authors: tang q. J Exp Med. 2021 Aug 2;218(8):e20210759. doi: 10.1084/jem.20210759. Epub 2021 Jun 11. J Exp Med. 2021. PMID: 34115115 Free PMC article.
Type 1 diabetes immunotherapy using polyclonal regulatory T cells.
Bluestone JA, Buckner JH, Fitch M, Gitelman SE, Gupta S, Hellerstein MK, Herold KC, Lares A, Lee MR, Li K, Liu W, Long SA, Masiello LM, Nguyen V, Putnam AL, Rieck M, Sayre PH, Tang Q. Bluestone JA, et al. Among authors: tang q. Sci Transl Med. 2015 Nov 25;7(315):315ra189. doi: 10.1126/scitranslmed.aad4134. Sci Transl Med. 2015. PMID: 26606968 Free PMC article. Clinical Trial.
Restoring Regulatory T Cells in Type 1 Diabetes.
Spence A, Tang Q. Spence A, et al. Among authors: tang q. Curr Diab Rep. 2016 Nov;16(11):110. doi: 10.1007/s11892-016-0807-6. Curr Diab Rep. 2016. PMID: 27664043 Review.
Revealing the specificity of regulatory T cells in murine autoimmune diabetes.
Spence A, Purtha W, Tam J, Dong S, Kim Y, Ju CH, Sterling T, Nakayama M, Robinson WH, Bluestone JA, Anderson MS, Tang Q. Spence A, et al. Among authors: tang q. Proc Natl Acad Sci U S A. 2018 May 15;115(20):5265-5270. doi: 10.1073/pnas.1715590115. Epub 2018 Apr 30. Proc Natl Acad Sci U S A. 2018. PMID: 29712852 Free PMC article.
Functional CRISPR dissection of gene networks controlling human regulatory T cell identity.
Schumann K, Raju SS, Lauber M, Kolb S, Shifrut E, Cortez JT, Skartsis N, Nguyen VQ, Woo JM, Roth TL, Yu R, Nguyen MLT, Simeonov DR, Nguyen DN, Targ S, Gate RE, Tang Q, Bluestone JA, Spitzer MH, Ye CJ, Marson A. Schumann K, et al. Among authors: tang q. Nat Immunol. 2020 Nov;21(11):1456-1466. doi: 10.1038/s41590-020-0784-4. Epub 2020 Sep 28. Nat Immunol. 2020. PMID: 32989329 Free PMC article.
The effect of low-dose IL-2 and Treg adoptive cell therapy in patients with type 1 diabetes.
Dong S, Hiam-Galvez KJ, Mowery CT, Herold KC, Gitelman SE, Esensten JH, Liu W, Lares AP, Leinbach AS, Lee M, Nguyen V, Tamaki SJ, Tamaki W, Tamaki CM, Mehdizadeh M, Putnam AL, Spitzer MH, Ye CJ, Tang Q, Bluestone JA. Dong S, et al. Among authors: tang q. JCI Insight. 2021 Sep 22;6(18):e147474. doi: 10.1172/jci.insight.147474. JCI Insight. 2021. PMID: 34324441 Free PMC article. Clinical Trial.
7,757 results