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Optimization of the clofazimine structure leads to a highly water-soluble C3-aminopyridinyl riminophenazine endowed with improved anti-Wnt and anti-cancer activity in vitro and in vivo.
Koval A, Bassanini I, Xu J, Tonelli M, Boido V, Sparatore F, Amant F, Annibali D, Leucci E, Sparatore A, Katanaev VL. Koval A, et al. Among authors: xu j. Eur J Med Chem. 2021 Oct 15;222:113562. doi: 10.1016/j.ejmech.2021.113562. Epub 2021 May 30. Eur J Med Chem. 2021. PMID: 34116325 Free article.
Wnt-Independent SARS-CoV-2 Infection in Pulmonary Epithelial Cells.
Koval A, Xu J, Williams N, Schmolke M, Krause KH, Katanaev VL. Koval A, et al. Among authors: xu j. Microbiol Spectr. 2023 Aug 17;11(4):e0482722. doi: 10.1128/spectrum.04827-22. Epub 2023 Jun 27. Microbiol Spectr. 2023. PMID: 37367224 Free PMC article.
Clofazimine: A journey of a drug.
Xu J, Koval A, Katanaev VL. Xu J, et al. Biomed Pharmacother. 2023 Nov;167:115539. doi: 10.1016/j.biopha.2023.115539. Epub 2023 Sep 22. Biomed Pharmacother. 2023. PMID: 37742606 Free article. Review.
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