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Comparable Genital Tract Infection, Pathology, and Immunity in Rhesus Macaques Inoculated with Wild-Type or Plasmid-Deficient Chlamydia trachomatis Serovar D.
Qu Y, Frazer LC, O'Connell CM, Tarantal AF, Andrews CW Jr, O'Connor SL, Russell AN, Sullivan JE, Poston TB, Vallejo AN, Darville T. Qu Y, et al. Among authors: andrews cw jr. Infect Immun. 2015 Oct;83(10):4056-67. doi: 10.1128/IAI.00841-15. Epub 2015 Jul 27. Infect Immun. 2015. PMID: 26216426 Free PMC article.
IL-23 induces IL-22 and IL-17 production in response to Chlamydia muridarum genital tract infection, but the absence of these cytokines does not influence disease pathogenesis.
Frazer LC, Scurlock AM, Zurenski MA, Riley MM, Mintus M, Pociask DA, Sullivan JE, Andrews CW Jr, Darville T. Frazer LC, et al. Among authors: andrews cw jr. Am J Reprod Immunol. 2013 Dec;70(6):472-84. doi: 10.1111/aji.12171. Am J Reprod Immunol. 2013. PMID: 24238108 Free PMC article.
Interleukin-17 contributes to generation of Th1 immunity and neutrophil recruitment during Chlamydia muridarum genital tract infection but is not required for macrophage influx or normal resolution of infection.
Scurlock AM, Frazer LC, Andrews CW Jr, O'Connell CM, Foote IP, Bailey SL, Chandra-Kuntal K, Kolls JK, Darville T. Scurlock AM, et al. Among authors: andrews cw jr. Infect Immun. 2011 Mar;79(3):1349-62. doi: 10.1128/IAI.00984-10. Epub 2010 Dec 13. Infect Immun. 2011. PMID: 21149587 Free PMC article.
MyD88 deficiency leads to decreased NK cell gamma interferon production and T cell recruitment during Chlamydia muridarum genital tract infection, but a predominant Th1 response and enhanced monocytic inflammation are associated with infection resolution.
Nagarajan UM, Sikes J, Prantner D, Andrews CW Jr, Frazer L, Goodwin A, Snowden JN, Darville T. Nagarajan UM, et al. Among authors: andrews cw jr. Infect Immun. 2011 Jan;79(1):486-98. doi: 10.1128/IAI.00843-10. Epub 2010 Nov 15. Infect Immun. 2011. PMID: 21078858 Free PMC article.
31 results