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Induction of antigen-specific tolerance by nanobody-antigen adducts that target class-II major histocompatibility complexes.
Pishesha N, Harmand T, Smeding LY, Ma W, Ludwig LS, Janssen R, Islam A, Xie YJ, Fang T, McCaul N, Pinney W 3rd, Sugito HR, Rossotti MA, Gonzalez-Sapienza G, Ploegh HL. Pishesha N, et al. Among authors: harmand t. Nat Biomed Eng. 2021 Nov;5(11):1389-1401. doi: 10.1038/s41551-021-00738-5. Epub 2021 Jun 14. Nat Biomed Eng. 2021. PMID: 34127819
A guide to antigen processing and presentation.
Pishesha N, Harmand TJ, Ploegh HL. Pishesha N, et al. Among authors: harmand tj. Nat Rev Immunol. 2022 Dec;22(12):751-764. doi: 10.1038/s41577-022-00707-2. Epub 2022 Apr 13. Nat Rev Immunol. 2022. PMID: 35418563 Review.
Nanobodies as in vivo, non-invasive, imaging agents.
Harmand TJ, Islam A, Pishesha N, Ploegh HL. Harmand TJ, et al. RSC Chem Biol. 2021 Mar 8;2(3):685-701. doi: 10.1039/d1cb00023c. RSC Chem Biol. 2021. PMID: 34212147 Free PMC article. Review.
A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants.
Pishesha N, Harmand TJ, Rothlauf PW, Praest P, Alexander RK, van den Doel R, Liebeskind MJ, Vakaki MA, McCaul N, Wijne C, Verhaar E, Pinney W 3rd, Heston H, Bloyet LM, Pontelli MC, Ilagan MXG, Jan Lebbink R, Buchser WJ, Wiertz EJHJ, Whelan SPJ, Ploegh HL. Pishesha N, et al. Among authors: harmand tj. Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2116147118. doi: 10.1073/pnas.2116147118. Proc Natl Acad Sci U S A. 2021. PMID: 34654739 Free PMC article.
Exploring cellular biochemistry with nanobodies.
Cheloha RW, Harmand TJ, Wijne C, Schwartz TU, Ploegh HL. Cheloha RW, et al. Among authors: harmand tj. J Biol Chem. 2020 Nov 6;295(45):15307-15327. doi: 10.1074/jbc.REV120.012960. Epub 2020 Aug 31. J Biol Chem. 2020. PMID: 32868455 Free PMC article. Review.
16 results