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Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis.
Winnick JJ, Kraft G, Gregory JM, Edgerton DS, Williams P, Hajizadeh IA, Kamal MZ, Smith M, Farmer B, Scott M, Neal D, Donahue EP, Allen E, Cherrington AD. Winnick JJ, et al. Among authors: gregory jm. J Clin Invest. 2016 Jun 1;126(6):2236-48. doi: 10.1172/JCI79895. Epub 2016 May 3. J Clin Invest. 2016. PMID: 27140398 Free PMC article.
Glucose autoregulation is the dominant component of the hormone-independent counterregulatory response to hypoglycemia in the conscious dog.
Gregory JM, Rivera N, Kraft G, Winnick JJ, Farmer B, Allen EJ, Donahue EP, Smith MS, Edgerton DS, Williams PE, Cherrington AD. Gregory JM, et al. Am J Physiol Endocrinol Metab. 2017 Sep 1;313(3):E273-E283. doi: 10.1152/ajpendo.00099.2017. Epub 2017 May 16. Am J Physiol Endocrinol Metab. 2017. PMID: 28512154 Free PMC article.
Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison With GCK-MODY (MODY2).
Gregory JM, Smith TJ, Slaughter JC, Mason HR, Hughey CC, Smith MS, Kandasamy B, Greeley SAW, Philipson LH, Naylor RN, Letourneau LR, Abumrad NN, Cherrington AD, Moore DJ. Gregory JM, et al. Diabetes. 2019 Aug;68(8):1565-1576. doi: 10.2337/db19-0324. Epub 2019 May 15. Diabetes. 2019. PMID: 31092478 Free PMC article.
Peripherally delivered hepatopreferential insulin analog insulin-406 mimics the hypoglycaemia-sparing effect of portal vein human insulin infusion in dogs.
Gregory JM, Kraft G, Scott MF, Neal DW, Farmer B, Smith MS, Hastings JR, Madsen P, Kjeldsen TB, Hostrup S, Brand CL, Fledelius C, Nishimura E, Cherrington AD. Gregory JM, et al. Diabetes Obes Metab. 2019 Oct;21(10):2294-2304. doi: 10.1111/dom.13808. Epub 2019 Jul 8. Diabetes Obes Metab. 2019. PMID: 31183936 Free PMC article.
119 results