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Mind the GAP: Wnt steps onto the mTORC1 train.
Choo AY, Roux PP, Blenis J. Choo AY, et al. Among authors: blenis j. Cell. 2006 Sep 8;126(5):834-6. doi: 10.1016/j.cell.2006.08.025. Cell. 2006. PMID: 16959561 Free article.
Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.
Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, Lee TH, Asara JM, Manning BD, Blenis J, Su B, Wei W. Liu P, et al. Among authors: blenis j. Nat Cell Biol. 2013 Nov;15(11):1340-50. doi: 10.1038/ncb2860. Epub 2013 Oct 27. Nat Cell Biol. 2013. PMID: 24161930 Free PMC article.
ERK2 Mediates Metabolic Stress Response to Regulate Cell Fate.
Shin S, Buel GR, Wolgamott L, Plas DR, Asara JM, Blenis J, Yoon SO. Shin S, et al. Among authors: blenis j. Mol Cell. 2015 Aug 6;59(3):382-98. doi: 10.1016/j.molcel.2015.06.020. Epub 2015 Jul 16. Mol Cell. 2015. PMID: 26190261 Free PMC article.
Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.
Mullarky E, Lucki NC, Beheshti Zavareh R, Anglin JL, Gomes AP, Nicolay BN, Wong JC, Christen S, Takahashi H, Singh PK, Blenis J, Warren JD, Fendt SM, Asara JM, DeNicola GM, Lyssiotis CA, Lairson LL, Cantley LC. Mullarky E, et al. Among authors: blenis j. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1778-83. doi: 10.1073/pnas.1521548113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831078 Free PMC article.
249 results