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Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation.
Orth MF, Surdez D, Faehling T, Ehlers AC, Marchetto A, Grossetête S, Volckmann R, Zwijnenburg DA, Gerke JS, Zaidi S, Alonso J, Sastre A, Baulande S, Sill M, Cidre-Aranaz F, Ohmura S, Kirchner T, Hauck SM, Reischl E, Gymrek M, Pfister SM, Strauch K, Koster J, Delattre O, Grünewald TGP. Orth MF, et al. Among authors: surdez d. Cell Rep. 2022 Dec 6;41(10):111761. doi: 10.1016/j.celrep.2022.111761. Cell Rep. 2022. PMID: 36476851 Free PMC article.
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance.
Danielli SG, Porpiglia E, De Micheli AJ, Navarro N, Zellinger MJ, Bechtold I, Kisele S, Volken L, Marques JG, Kasper S, Bode PK, Henssen AG, Gürgen D, Delattre O, Surdez D, Roma J, Bühlmann P, Blau HM, Wachtel M, Schäfer BW. Danielli SG, et al. Among authors: surdez d. Sci Adv. 2023 Feb 10;9(6):eade9238. doi: 10.1126/sciadv.ade9238. Epub 2023 Feb 8. Sci Adv. 2023. PMID: 36753540 Free PMC article.
Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution.
Aynaud MM, Mirabeau O, Gruel N, Grossetête S, Boeva V, Durand S, Surdez D, Saulnier O, Zaïdi S, Gribkova S, Fouché A, Kairov U, Raynal V, Tirode F, Grünewald TGP, Bohec M, Baulande S, Janoueix-Lerosey I, Vert JP, Barillot E, Delattre O, Zinovyev A. Aynaud MM, et al. Among authors: surdez d. Cell Rep. 2020 Feb 11;30(6):1767-1779.e6. doi: 10.1016/j.celrep.2020.01.049. Cell Rep. 2020. PMID: 32049009 Free article.
Ewing Sarcoma PDX Models.
Surdez D, Landuzzi L, Scotlandi K, Manara MC. Surdez D, et al. Methods Mol Biol. 2021;2226:223-242. doi: 10.1007/978-1-0716-1020-6_18. Methods Mol Biol. 2021. PMID: 33326106
Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions.
Vibert J, Saulnier O, Collin C, Petit F, Borgman KJE, Vigneau J, Gautier M, Zaidi S, Pierron G, Watson S, Gruel N, Hénon C, Postel-Vinay S, Deloger M, Raynal V, Baulande S, Laud-Duval K, Hill V, Grossetête S, Dingli F, Loew D, Torrejon J, Ayrault O, Orth MF, Grünewald TGP, Surdez D, Coulon A, Waterfall JJ, Delattre O. Vibert J, et al. Among authors: surdez d. Mol Cell. 2022 Jul 7;82(13):2458-2471.e9. doi: 10.1016/j.molcel.2022.04.019. Epub 2022 May 11. Mol Cell. 2022. PMID: 35550257 Free article.
Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts.
Sturtzel C, Grissenberger S, Bozatzi P, Scheuringer E, Wenninger-Weinzierl A, Zajec Z, Dernovšek J, Pascoal S, Gehl V, Kutsch A, Granig A, Rifatbegovic F, Carre M, Lang A, Valtingojer I, Moll J, Lötsch D, Erhart F, Widhalm G, Surdez D, Delattre O, André N, Stampfl J, Tomašič T, Taschner-Mandl S, Distel M. Sturtzel C, et al. Among authors: surdez d. NPJ Precis Oncol. 2023 May 18;7(1):44. doi: 10.1038/s41698-023-00386-9. NPJ Precis Oncol. 2023. PMID: 37202469 Free PMC article. Review.
SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance.
Vokshi BH, Davidson G, Tawanaie Pour Sedehi N, Helleux A, Rippinger M, Haller AR, Gantzer J, Thouvenin J, Baltzinger P, Bouarich R, Manriquez V, Zaidi S, Rao P, Msaouel P, Su X, Lang H, Tricard T, Lindner V, Surdez D, Kurtz JE, Bourdeaut F, Tannir NM, Davidson I, Malouf GG. Vokshi BH, et al. Among authors: surdez d. Nat Commun. 2023 May 26;14(1):3034. doi: 10.1038/s41467-023-38472-y. Nat Commun. 2023. PMID: 37236926 Free PMC article.
66 results