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Design, Synthesis, In Vitro and In Vivo Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down Syndrome.
Borgogno M, Savardi A, Manigrasso J, Turci A, Portioli C, Ottonello G, Bertozzi SM, Armirotti A, Contestabile A, Cancedda L, De Vivo M. Borgogno M, et al. Among authors: portioli c. J Med Chem. 2021 Jul 22;64(14):10203-10229. doi: 10.1021/acs.jmedchem.1c00603. Epub 2021 Jun 17. J Med Chem. 2021. PMID: 34137257 Free PMC article.
BEAR, a novel virtual screening methodology for drug discovery.
Degliesposti G, Portioli C, Parenti MD, Rastelli G. Degliesposti G, et al. Among authors: portioli c. J Biomol Screen. 2011 Jan;16(1):129-33. doi: 10.1177/1087057110388276. Epub 2010 Nov 17. J Biomol Screen. 2011. PMID: 21084717 Free article.
Cation Chloride Cotransporter NKCC1 Operates through a Rocking-Bundle Mechanism.
Ruiz Munevar MJ, Rizzi V, Portioli C, Vidossich P, Cao E, Parrinello M, Cancedda L, De Vivo M. Ruiz Munevar MJ, et al. Among authors: portioli c. J Am Chem Soc. 2024 Jan 10;146(1):552-566. doi: 10.1021/jacs.3c10258. Epub 2023 Dec 25. J Am Chem Soc. 2024. PMID: 38146212 Free PMC article.
12 results