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Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells.
Shaim H, Shanley M, Basar R, Daher M, Gumin J, Zamler DB, Uprety N, Wang F, Huang Y, Gabrusiewicz K, Miao Q, Dou J, Alsuliman A, Kerbauy LN, Acharya S, Mohanty V, Mendt M, Li S, Lu J, Wei J, Fowlkes NW, Gokdemir E, Ensley EL, Kaplan M, Kassab C, Li L, Ozcan G, Banerjee PP, Shen Y, Gilbert AL, Jones CM, Bdiwi M, Nunez-Cortes AK, Liu E, Yu J, Imahashi N, Muniz-Feliciano L, Li Y, Hu J, Draetta G, Marin D, Yu D, Mielke S, Eyrich M, Champlin RE, Chen K, Lang FF, Shpall EJ, Heimberger AB, Rezvani K. Shaim H, et al. Among authors: huang y. J Clin Invest. 2021 Jul 15;131(14):e142116. doi: 10.1172/JCI142116. J Clin Invest. 2021. PMID: 34138753 Free PMC article.
Decoupling Lineage-Associated Genes in Acute Myeloid Leukemia Reveals Inflammatory and Metabolic Signatures Associated With Outcomes.
Abbas HA, Mohanty V, Wang R, Huang Y, Liang S, Wang F, Zhang J, Qiu Y, Hu CW, Qutub AA, Dail M, Bolen CR, Daver N, Konopleva M, Futreal A, Chen K, Wang L, Kornblau SM. Abbas HA, et al. Among authors: huang y. Front Oncol. 2021 Aug 4;11:705627. doi: 10.3389/fonc.2021.705627. eCollection 2021. Front Oncol. 2021. PMID: 34422660 Free PMC article.
Sensei: how many samples to tell a change in cell type abundance?
Liang S, Willis J, Dou J, Mohanty V, Huang Y, Vilar E, Chen K. Liang S, et al. Among authors: huang y. BMC Bioinformatics. 2022 Jan 4;23(1):2. doi: 10.1186/s12859-021-04526-5. BMC Bioinformatics. 2022. PMID: 34983369 Free PMC article.
Bi-order multimodal integration of single-cell data.
Dou J, Liang S, Mohanty V, Miao Q, Huang Y, Liang Q, Cheng X, Kim S, Choi J, Li Y, Li L, Daher M, Basar R, Rezvani K, Chen R, Chen K. Dou J, et al. Among authors: huang y. Genome Biol. 2022 May 9;23(1):112. doi: 10.1186/s13059-022-02679-x. Genome Biol. 2022. PMID: 35534898 Free PMC article.
Activated B cells suppress T-cell function through metabolic competition.
Imahashi N, Basar R, Huang Y, Wang F, Baran N, Banerjee PP, Lu J, Nunez Cortes AK, Uprety N, Ensley E, Muniz-Feliciano L, Laskowski TJ, Moyes JS, Daher M, Mendt M, Kerbauy LN, Shanley M, Li L, Lim FLWI, Shaim H, Li Y, Konopleva M, Green M, Wargo J, Shpall EJ, Chen K, Rezvani K. Imahashi N, et al. Among authors: huang y. J Immunother Cancer. 2022 Dec;10(12):e005644. doi: 10.1136/jitc-2022-005644. J Immunother Cancer. 2022. PMID: 36543374 Free PMC article.
Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering.
Li L, Mohanty V, Dou J, Huang Y, Banerjee PP, Miao Q, Lohr JG, Vijaykumar T, Frede J, Knoechel B, Muniz-Feliciano L, Laskowski TJ, Liang S, Moyes JS, Nandivada V, Basar R, Kaplan M, Daher M, Liu E, Li Y, Acharya S, Lin P, Shanley M, Rafei H, Marin D, Mielke S, Champlin RE, Shpall EJ, Chen K, Rezvani K. Li L, et al. Among authors: huang y. Sci Adv. 2023 Jul 28;9(30):eadd6997. doi: 10.1126/sciadv.add6997. Epub 2023 Jul 26. Sci Adv. 2023. PMID: 37494448 Free PMC article.
Clinical and Molecular Characterization of POLE Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers.
Garmezy B, Gheeya J, Lin HY, Huang Y, Kim T, Jiang X, Thein KZ, Pilié PG, Zeineddine F, Wang W, Shaw KR, Rodon J, Shen JP, Yuan Y, Meric-Bernstam F, Chen K, Yap TA. Garmezy B, et al. Among authors: huang y. JCO Precis Oncol. 2022 Feb;6:e2100267. doi: 10.1200/PO.21.00267. JCO Precis Oncol. 2022. PMID: 35108036 Free PMC article.
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