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Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer's disease (TOMMORROW): a prognostic biomarker study and a phase 3, randomised, double-blind, placebo-controlled trial.
Burns DK, Alexander RC, Welsh-Bohmer KA, Culp M, Chiang C, O'Neil J, Evans RM, Harrigan P, Plassman BL, Burke JR, Wu J, Lutz MW, Haneline S, Schwarz AJ, Schneider LS, Yaffe K, Saunders AM, Ratti E; TOMMORROW study investigators. Burns DK, et al. Among authors: saunders am. Lancet Neurol. 2021 Jul;20(7):537-547. doi: 10.1016/S1474-4422(21)00043-0. Lancet Neurol. 2021. PMID: 34146512 Clinical Trial.
New applications of disease genetics and pharmacogenetics to drug development.
Roses AD, Saunders AM, Lutz MW, Zhang N, Hariri AR, Asin KE, Crenshaw DG, Budur K, Burns DK, Brannan SK. Roses AD, et al. Among authors: saunders am. Curr Opin Pharmacol. 2014 Feb;14:81-9. doi: 10.1016/j.coph.2013.12.002. Epub 2014 Jan 3. Curr Opin Pharmacol. 2014. PMID: 24565016 Free article. Review.
The TOMMORROW study: Design of an Alzheimer's disease delay-of-onset clinical trial.
Burns DK, Chiang C, Welsh-Bohmer KA, Brannan SK, Culp M, O'Neil J, Runyan G, Harrigan P, Plassman BL, Lutz M, Lai E, Haneline S, Yarnall D, Yarbrough D, Metz C, Ponduru S, Sundseth S, Saunders AM. Burns DK, et al. Among authors: saunders am. Alzheimers Dement (N Y). 2019 Oct 28;5:661-670. doi: 10.1016/j.trci.2019.09.010. eCollection 2019. Alzheimers Dement (N Y). 2019. PMID: 31720367 Free PMC article.
Reassessment of Pioglitazone for Alzheimer's Disease.
Saunders AM, Burns DK, Gottschalk WK. Saunders AM, et al. Front Neurosci. 2021 Jun 16;15:666958. doi: 10.3389/fnins.2021.666958. eCollection 2021. Front Neurosci. 2021. PMID: 34220427 Free PMC article. Review.
Using genetics to enable studies on the prevention of Alzheimer's disease.
Crenshaw DG, Gottschalk WK, Lutz MW, Grossman I, Saunders AM, Burke JR, Welsh-Bohmer KA, Brannan SK, Burns DK, Roses AD. Crenshaw DG, et al. Among authors: saunders am. Clin Pharmacol Ther. 2013 Feb;93(2):177-85. doi: 10.1038/clpt.2012.222. Epub 2012 Nov 7. Clin Pharmacol Ther. 2013. PMID: 23249780 Free PMC article.
283 results