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Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer's disease (TOMMORROW): a prognostic biomarker study and a phase 3, randomised, double-blind, placebo-controlled trial.
Burns DK, Alexander RC, Welsh-Bohmer KA, Culp M, Chiang C, O'Neil J, Evans RM, Harrigan P, Plassman BL, Burke JR, Wu J, Lutz MW, Haneline S, Schwarz AJ, Schneider LS, Yaffe K, Saunders AM, Ratti E; TOMMORROW study investigators. Burns DK, et al. Among authors: schwarz aj. Lancet Neurol. 2021 Jul;20(7):537-547. doi: 10.1016/S1474-4422(21)00043-0. Lancet Neurol. 2021. PMID: 34146512 Clinical Trial.
Volumetric MRI-Based Biomarkers in Huntington's Disease: An Evidentiary Review.
Kinnunen KM, Schwarz AJ, Turner EC, Pustina D, Gantman EC, Gordon MF, Joules R, Mullin AP, Scahill RI, Georgiou-Karistianis N; Huntington's Disease Regulatory Science Consortium (HD-RSC). Kinnunen KM, et al. Among authors: schwarz aj. Front Neurol. 2021 Sep 21;12:712555. doi: 10.3389/fneur.2021.712555. eCollection 2021. Front Neurol. 2021. PMID: 34621236 Free PMC article. Review.
Identifying individuals with non-Alzheimer's disease co-pathologies: A precision medicine approach to clinical trials in sporadic Alzheimer's disease.
Tosun D, Yardibi O, Benzinger TLS, Kukull WA, Masters CL, Perrin RJ, Weiner MW, Simen A, Schwarz AJ; Alzheimer's Disease Neuroimaging Initiative. Tosun D, et al. Among authors: schwarz aj. Alzheimers Dement. 2024 Jan;20(1):421-436. doi: 10.1002/alz.13447. Epub 2023 Sep 4. Alzheimers Dement. 2024. PMID: 37667412 Free PMC article.
Criterion Validation of Tau PET Staging Schemes in Relation to Cognitive Outcomes.
Hammers DB, Lin JH, Polsinelli AJ, Logan PE, Risacher SL, Schwarz AJ, Apostolova LG; Alzheimer’s Disease Neuroimaging Initiative. Hammers DB, et al. Among authors: schwarz aj. J Alzheimers Dis. 2023;96(1):197-214. doi: 10.3233/JAD-230512. J Alzheimers Dis. 2023. PMID: 37742649 Free PMC article.
A natural history study to track brain and spinal cord changes in individuals with Friedreich's ataxia: TRACK-FA study protocol.
Georgiou-Karistianis N, Corben LA, Reetz K, Adanyeguh IM, Corti M, Deelchand DK, Delatycki MB, Dogan I, Evans R, Farmer J, França MC, Gaetz W, Harding IH, Harris KS, Hersch S, Joules R, Joers JJ, Krishnan ML, Lax M, Lock EF, Lynch D, Mareci T, Muthuhetti Gamage S, Pandolfo M, Papoutsi M, Rezende TJR, Roberts TPL, Rosenberg JT, Romanzetti S, Schulz JB, Schilling T, Schwarz AJ, Subramony S, Yao B, Zicha S, Lenglet C, Henry PG. Georgiou-Karistianis N, et al. Among authors: schwarz aj. PLoS One. 2022 Nov 21;17(11):e0269649. doi: 10.1371/journal.pone.0269649. eCollection 2022. PLoS One. 2022. PMID: 36410013 Free PMC article. Clinical Trial.
Association of Vascular Risk Factors and Cerebrovascular Pathology With Alzheimer Disease Pathologic Changes in Individuals Without Dementia.
Lorenzini L, Maranzano A, Ingala S, Collij LE, Tranfa M, Blennow K, Di Perri C, Foley C, Fox NC, Frisoni GB, Haller S, Martinez-Lage P, Mollison D, O'Brien J, Payoux P, Ritchie C, Scheltens P, Schwarz AJ, Sudre CH, Tijms BM, Verde F, Ticozzi N, Silani V, Visser PJ, Waldman A, Wolz R, Chételat G, Ewers M, Wink AM, Mutsaerts H, Gispert JD, Wardlaw JM, Barkhof F. Lorenzini L, et al. Among authors: schwarz aj. Neurology. 2024 Oct 8;103(7):e209801. doi: 10.1212/WNL.0000000000209801. Epub 2024 Sep 17. Neurology. 2024. PMID: 39288341 Free PMC article.
Diagnostic Validation of the Updated Pediatric Sepsis Biomarker Risk II for Acute Kidney Injury Prediction Model in Pediatric Septic Shock.
Stanski NL, Zhang B, Cvijanovich NZ, Fitzgerald JC, Bigham MT, Jain PN, Schwarz AJ, Lutfi R, Allen GL, Thomas NJ, Baines T, Haileselassie B, Weiss SL, Atreya MR, Lautz AJ, Zingarelli B, Standage SW, Kaplan J, Goldstein SL. Stanski NL, et al. Among authors: schwarz aj. Pediatr Crit Care Med. 2024 Nov 1;25(11):1005-1016. doi: 10.1097/PCC.0000000000003589. Epub 2024 Aug 6. Pediatr Crit Care Med. 2024. PMID: 39115853
Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non-demented individuals.
Lorenzini L, Collij LE, Tesi N, Vilor-Tejedor N, Ingala S, Blennow K, Foley C, Frisoni GB, Haller S, Holstege H, van der van der Lee S, Martinez-Lage P, Marioni RE, McCartney DL, O' Brien J, Oliveira TG, Payoux P, Reinders M, Ritchie C, Scheltens P, Schwarz AJ, Sudre CH, Waldman AD, Wolz R, Chatelat G, Ewers M, Wink AM, Mutsaerts HJMM, Gispert JD, Visser PJ, Tijms BM, Altmann A, Barkhof F. Lorenzini L, et al. Among authors: schwarz aj. Alzheimers Dement. 2024 Sep;20(9):6146-6160. doi: 10.1002/alz.14096. Epub 2024 Jul 29. Alzheimers Dement. 2024. PMID: 39073684 Free PMC article.
Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer's disease.
Beckman D, Diniz GB, Ott S, Hobson B, Chaudhari AJ, Muller S, Chu Y, Takano A, Schwarz AJ, Yeh CL, McQuade P, Chakrabarty P, Kanaan NM, Quinton MS, Simen AA, Kordower JH, Morrison JH. Beckman D, et al. Among authors: schwarz aj. Alzheimers Dement. 2024 Aug;20(8):5198-5219. doi: 10.1002/alz.13868. Epub 2024 Jun 21. Alzheimers Dement. 2024. PMID: 39030748 Free PMC article.
188 results