Dukes G - Search Results

1

Randomised clinical trial: safety, pharmacokinetics and pharmacodynamics of trazpiroben (TAK-906), a dopamine D₂ /D₃ receptor antagonist, in patients with gastroparesis.

Kuo B, Scimia C, Dukes G, Zhang W, Gupta S, Chen C, Chuang E, Camilleri M. Kuo B, et al. Among authors: dukes g. Aliment Pharmacol Ther. 2021 Aug;54(3):267-280. doi: 10.1111/apt.16451. Epub 2021 Jun 20. Aliment Pharmacol Ther. 2021. PMID: 34148244 Clinical Trial.

2

Randomised study: effects of the 5-HT₄ receptor agonist felcisetrag vs placebo on gut transit in patients with gastroparesis.

Chedid V, Brandler J, Arndt K, Vijayvargiya P, Wang XJ, Burton D, Harmsen WS, Siegelman J, Chen C, Chen Y, Almansa C, Dukes G, Camilleri M. Chedid V, et al. Among authors: dukes g. Aliment Pharmacol Ther. 2021 May;53(9):1010-1020. doi: 10.1111/apt.16304. Epub 2021 Mar 12. Aliment Pharmacol Ther. 2021. PMID: 33711180 Free PMC article. Clinical Trial.

3

Evaluation of the pharmacokinetics of trazpiroben (TAK-906) in the presence and absence of the proton pump inhibitor esomeprazole.

Kaur Mukker J, Dukes G, Wang L, Huh S, Khudyakov P, Nishihara M, Chen C. Kaur Mukker J, et al. Among authors: dukes g. Clin Transl Sci. 2022 May;15(5):1281-1290. doi: 10.1111/cts.13248. Epub 2022 Feb 26. Clin Transl Sci. 2022. PMID: 35218604 Free PMC article.

4

The pharmacokinetics of oral trazpiroben (TAK-906) after organic anion transporting polypeptide 1B1/1B3 inhibition: A phase I, randomized study.

Mukker JK, Dukes G, Tolkoff M, Wang L, Almansa C, Huh SY, Nishihara M, Ramsden D, Chen C. Mukker JK, et al. Among authors: dukes g. Clin Transl Sci. 2022 Jun;15(6):1532-1543. doi: 10.1111/cts.13274. Epub 2022 May 5. Clin Transl Sci. 2022. PMID: 35460165 Free PMC article. Clinical Trial.

5

The Effect of Hepatic Impairment on the Pharmacokinetics of Intravenously Administered Felcisetrag (TAK-954).

Czerniak R, Cieslarová B, Kupčová V, Rosario M, Lock R, Dong C, Dukes G. Czerniak R, et al. Among authors: dukes g. J Clin Pharmacol. 2022 Aug;62(8):1006-1017. doi: 10.1002/jcph.2044. Epub 2022 Mar 31. J Clin Pharmacol. 2022. PMID: 35253917 Free PMC article. Clinical Trial.

6

Incidence, Risk Factors, and Clinical Consequence of Enteral Feeding Intolerance in the Mechanically Ventilated Critically Ill: An Analysis of a Multicenter, Multiyear Database.

Heyland DK, Ortiz A, Stoppe C, Patel JJ, Yeh DD, Dukes G, Chen YJ, Almansa C, Day AG. Heyland DK, et al. Among authors: dukes g. Crit Care Med. 2021 Jan 1;49(1):49-59. doi: 10.1097/CCM.0000000000004712. Crit Care Med. 2021. PMID: 33148950

7

Prevalence, risk factors, clinical consequences, and treatment of enteral feed intolerance during critical illness.

Gungabissoon U, Hacquoil K, Bains C, Irizarry M, Dukes G, Williamson R, Deane AM, Heyland DK. Gungabissoon U, et al. Among authors: dukes g. JPEN J Parenter Enteral Nutr. 2015 May;39(4):441-8. doi: 10.1177/0148607114526450. Epub 2014 Mar 17. JPEN J Parenter Enteral Nutr. 2015. PMID: 24637246

8

A semi-mechanistic gastric emptying model for the population pharmacokinetic analysis of orally administered acetaminophen in critically ill patients.

Ogungbenro K, Vasist L, Maclaren R, Dukes G, Young M, Aarons L. Ogungbenro K, et al. Among authors: dukes g. Pharm Res. 2011 Feb;28(2):394-404. doi: 10.1007/s11095-010-0290-8. Epub 2010 Oct 15. Pharm Res. 2011. PMID: 20949310

9

Determination of release limits: a general methodology.

Allen PV, Dukes GR, Gerger ME. Allen PV, et al. Among authors: dukes gr. Pharm Res. 1991 Sep;8(9):1210-3. doi: 10.1023/a:1015879107574. Pharm Res. 1991. PMID: 1788171

10

A randomized phase 2 study of the 5-HT₄ receptor agonist felcisetrag for postoperative gastrointestinal dysfunction after bowel surgery.

Boeckxstaens G, Ayad S, Dukes G, Essandoh M, Gryder R, Kamble P, Tackett J, Thakker P, Williams J, Zhang Y, Wade PR. Boeckxstaens G, et al. Among authors: dukes g. Am J Surg. 2024 Aug;234:162-171. doi: 10.1016/j.amjsurg.2024.04.030. Epub 2024 Apr 27. Am J Surg. 2024. PMID: 38724293 Free article. Clinical Trial.

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