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The Macrophage Response Is Driven by Mesenchymal Stem Cell-Mediated Metabolic Reprogramming.
Luque-Campos N, Bustamante-Barrientos FA, Pradenas C, García C, Araya MJ, Bohaud C, Contreras-López R, Elizondo-Vega R, Djouad F, Luz-Crawford P, Vega-Letter AM. Luque-Campos N, et al. Among authors: contreras lopez r. Front Immunol. 2021 Jun 4;12:624746. doi: 10.3389/fimmu.2021.624746. eCollection 2021. Front Immunol. 2021. PMID: 34149687 Free PMC article. Review.
HIF1α-dependent metabolic reprogramming governs mesenchymal stem/stromal cell immunoregulatory functions.
Contreras-Lopez R, Elizondo-Vega R, Paredes MJ, Luque-Campos N, Torres MJ, Tejedor G, Vega-Letter AM, Figueroa-Valdés A, Pradenas C, Oyarce K, Jorgensen C, Khoury M, Garcia-Robles MLA, Altamirano C, Djouad F, Luz-Crawford P. Contreras-Lopez R, et al. FASEB J. 2020 Jun;34(6):8250-8264. doi: 10.1096/fj.201902232R. Epub 2020 Apr 25. FASEB J. 2020. PMID: 32333618
PPARβ/δ-dependent MSC metabolism determines their immunoregulatory properties.
Contreras-Lopez RA, Elizondo-Vega R, Torres MJ, Vega-Letter AM, Luque-Campos N, Paredes-Martinez MJ, Pradenas C, Tejedor G, Oyarce K, Salgado M, Jorgensen C, Khoury M, Kronke G, Garcia-Robles MA, Altamirano C, Luz-Crawford P, Djouad F. Contreras-Lopez RA, et al. Sci Rep. 2020 Jul 10;10(1):11423. doi: 10.1038/s41598-020-68347-x. Sci Rep. 2020. PMID: 32651456 Free PMC article.
The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential.
Contreras-Lopez R, Elizondo-Vega R, Luque-Campos N, Torres MJ, Pradenas C, Tejedor G, Paredes-Martínez MJ, Vega-Letter AM, Campos-Mora M, Rigual-Gonzalez Y, Oyarce K, Salgado M, Jorgensen C, Khoury M, Garcia-Robles MLÁ, Altamirano C, Djouad F, Luz-Crawford P. Contreras-Lopez R, et al. Theranostics. 2021 Jan 1;11(1):445-460. doi: 10.7150/thno.51631. eCollection 2021. Theranostics. 2021. PMID: 33391485 Free PMC article.
Pyrroline-5-Carboxylate Reductase 1 Directs the Cartilage Protective and Regenerative Potential of Murphy Roths Large Mouse Mesenchymal Stem Cells.
Tejedor G, Contreras-Lopez R, Barthelaix A, Ruiz M, Noël D, De Ceuninck F, Pastoureau P, Luz-Crawford P, Jorgensen C, Djouad F. Tejedor G, et al. Among authors: contreras lopez r. Front Cell Dev Biol. 2021 Jul 2;9:604756. doi: 10.3389/fcell.2021.604756. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34277596 Free PMC article.
Human MuStem cells repress T-cell proliferation and cytotoxicity through both paracrine and contact-dependent pathways.
Charrier M, Lorant J, Contreras-Lopez R, Téjédor G, Blanquart C, Lieubeau B, Schleder C, Leroux I, Deshayes S, Fonteneau JF, Babarit C, Hamel A, Magot A, Péréon Y, Viau S, Delorme B, Luz-Crawford P, Lamirault G, Djouad F, Rouger K. Charrier M, et al. Among authors: contreras lopez r. Stem Cell Res Ther. 2022 Jan 10;13(1):7. doi: 10.1186/s13287-021-02681-3. Stem Cell Res Ther. 2022. PMID: 35012660 Free PMC article.
18 results