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TRPC1 intensifies house dust mite-induced airway remodeling by facilitating epithelial-to-mesenchymal transition and STAT3/NF-κB signaling.
Pu Q, Zhao Y, Sun Y, Huang T, Lin P, Zhou C, Qin S, Singh BB, Wu M. Pu Q, et al. Among authors: lin p. FASEB J. 2019 Jan;33(1):1074-1085. doi: 10.1096/fj.201801085R. Epub 2018 Aug 1. FASEB J. 2019. PMID: 30067380 Free PMC article.
Collectively, these findings identify TRPC1 as a modulator of HDM-induced airway remodeling via STAT3-mediated increase in mucus production, which provide new insight in our understanding of the molecular basis of airway remodeling, and identify novel therapeutic targets for inte …
Collectively, these findings identify TRPC1 as a modulator of HDM-induced airway remodeling via STAT3-mediated increase in mucus production, …
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