Schmitz JC - Search Results

1

Phase 1 study of safety, pharmacokinetics, and pharmacodynamics of tivantinib in combination with bevacizumab in adult patients with advanced solid tumors.

Maguire WF, Schmitz JC, Scemama J, Czambel K, Lin Y, Green AG, Wu S, Lin H, Puhalla S, Rhee J, Stoller R, Tawbi H, Lee JJ, Wright JJ, Beumer JH, Chu E, Appleman LJ; ETCTN-9153 Study Team. Maguire WF, et al. Among authors: schmitz jc. Cancer Chemother Pharmacol. 2021 Oct;88(4):643-654. doi: 10.1007/s00280-021-04317-y. Epub 2021 Jun 23. Cancer Chemother Pharmacol. 2021. PMID: 34164713 Free PMC article. Clinical Trial.

2

Effect of 2'-O-methyl antisense ORNs on expression of thymidylate synthase in human colon cancer RKO cells.

Schmitz JC, Yu D, Agrawal S, Chu E. Schmitz JC, et al. Nucleic Acids Res. 2001 Jan 15;29(2):415-22. doi: 10.1093/nar/29.2.415. Nucleic Acids Res. 2001. PMID: 11139611 Free PMC article.

3

Thymidylate synthase inhibitors as anticancer agents: from bench to bedside.

Chu E, Callender MA, Farrell MP, Schmitz JC. Chu E, et al. Among authors: schmitz jc. Cancer Chemother Pharmacol. 2003 Jul;52 Suppl 1:S80-9. doi: 10.1007/s00280-003-0625-9. Epub 2003 Jun 18. Cancer Chemother Pharmacol. 2003. PMID: 12819937 Review.

4

Characterization of a cis-acting regulatory element in the protein-coding region of human dihydrofolate reductase mRNA.

Tai N, Schmitz JC, Chen TM, Chu E. Tai N, et al. Among authors: schmitz jc. Biochem J. 2004 Mar 15;378(Pt 3):999-1006. doi: 10.1042/BJ20031396. Biochem J. 2004. PMID: 14664697 Free PMC article.

5

Small interfering double-stranded RNAs as therapeutic molecules to restore chemosensitivity to thymidylate synthase inhibitor compounds.

Schmitz JC, Chen TM, Chu E. Schmitz JC, et al. Cancer Res. 2004 Feb 15;64(4):1431-5. doi: 10.1158/0008-5472.can-03-1203. Cancer Res. 2004. PMID: 14973067

6

Regulation of p53 expression in response to 5-fluorouracil in human cancer RKO cells.

Ju J, Schmitz JC, Song B, Kudo K, Chu E. Ju J, et al. Among authors: schmitz jc. Clin Cancer Res. 2007 Jul 15;13(14):4245-51. doi: 10.1158/1078-0432.CCR-06-2890. Clin Cancer Res. 2007. PMID: 17634554

7

Effect of small interfering RNA 3'-end overhangs on chemosensitivity to thymidylate synthase inhibitors.

Schmitz JC, Chu E. Schmitz JC, et al. Silence. 2011 Jan 19;2(1):1. doi: 10.1186/1758-907X-2-1. Silence. 2011. PMID: 21247442 Free PMC article.

8

Total synthesis of (-)-CP2-disorazole C1.

Hopkins CD, Schmitz JC, Chu E, Wipf P. Hopkins CD, et al. Among authors: schmitz jc. Org Lett. 2011 Aug 5;13(15):4088-91. doi: 10.1021/ol2015994. Epub 2011 Jul 8. Org Lett. 2011. PMID: 21739942 Free PMC article.

9

Development of modified siRNA molecules incorporating 5-fluoro-2'-deoxyuridine residues to enhance cytotoxicity.

Wu SY, Chen TM, Gmeiner WH, Chu E, Schmitz JC. Wu SY, et al. Among authors: schmitz jc. Nucleic Acids Res. 2013 Apr;41(8):4650-9. doi: 10.1093/nar/gkt120. Epub 2013 Feb 28. Nucleic Acids Res. 2013. PMID: 23449220 Free PMC article.

10

Radiation therapy induces the DNA damage response in peripheral blood.

Bakkenist CJ, Czambel RK, Clump DA, Greenberger JS, Beumer JH, Schmitz JC. Bakkenist CJ, et al. Among authors: schmitz jc. Oncotarget. 2013 Aug;4(8):1143-8. doi: 10.18632/oncotarget.1084. Oncotarget. 2013. PMID: 23900392 Free PMC article.

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