Wu S - Search Results

1

Phase 1 study of safety, pharmacokinetics, and pharmacodynamics of tivantinib in combination with bevacizumab in adult patients with advanced solid tumors.

Maguire WF, Schmitz JC, Scemama J, Czambel K, Lin Y, Green AG, Wu S, Lin H, Puhalla S, Rhee J, Stoller R, Tawbi H, Lee JJ, Wright JJ, Beumer JH, Chu E, Appleman LJ; ETCTN-9153 Study Team. Maguire WF, et al. Among authors: wu s. Cancer Chemother Pharmacol. 2021 Oct;88(4):643-654. doi: 10.1007/s00280-021-04317-y. Epub 2021 Jun 23. Cancer Chemother Pharmacol. 2021. PMID: 34164713 Free PMC article. Clinical Trial.

2

Development of modified siRNA molecules incorporating 5-fluoro-2'-deoxyuridine residues to enhance cytotoxicity.

Wu SY, Chen TM, Gmeiner WH, Chu E, Schmitz JC. Wu SY, et al. Nucleic Acids Res. 2013 Apr;41(8):4650-9. doi: 10.1093/nar/gkt120. Epub 2013 Feb 28. Nucleic Acids Res. 2013. PMID: 23449220 Free PMC article.

3

The cytotoxic effects of regorafenib in combination with protein kinase D inhibition in human colorectal cancer cells.

Wei N, Chu E, Wu SY, Wipf P, Schmitz JC. Wei N, et al. Oncotarget. 2015 Mar 10;6(7):4745-56. doi: 10.18632/oncotarget.2938. Oncotarget. 2015. PMID: 25544765 Free PMC article.

4

Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells.

Wu S, Guo Z, Hopkins CD, Wei N, Chu E, Wipf P, Schmitz JC. Wu S, et al. Oncotarget. 2015 Dec 1;6(38):40866-79. doi: 10.18632/oncotarget.5885. Oncotarget. 2015. PMID: 26506423 Free PMC article.

5

Molecular subtypes of colorectal cancer in pre-clinical models show differential response to targeted therapies: Treatment implications beyond KRAS mutations.

Pal R, Wei N, Song N, Wu S, Kim RS, Wang Y, Gavin PG, Lucas PC, Srinivasan A, Allegra CJ, Jacobs SA, Paik S, Schmitz JC, Pogue-Geile KL. Pal R, et al. Among authors: wu s. PLoS One. 2018 Aug 17;13(8):e0200836. doi: 10.1371/journal.pone.0200836. eCollection 2018. PLoS One. 2018. PMID: 30118499 Free PMC article.

6

Discovery of [1,2,4]triazolo[4,3-a]pyridines as potent Smoothened inhibitors targeting the Hedgehog pathway with improved antitumor activity in vivo.

Tian N, Wu H, Zhang H, Yang D, Lv L, Yang Z, Zhang T, Quan D, Zhou L, Xie Y, Xu Y, Wei N, Zhang J, Chen M, Schmitz JC, Tian Y, Wu S. Tian N, et al. Among authors: wu h, wu s. Bioorg Med Chem. 2020 Aug 15;28(16):115584. doi: 10.1016/j.bmc.2020.115584. Epub 2020 Jun 15. Bioorg Med Chem. 2020. PMID: 32690258

7

The Combination of Scutellaria baicalensis Georgi and Sophora japonica L. ameliorate Renal Function by Regulating Gut Microbiota in Spontaneously Hypertensive Rats.

Guan Y, Chen K, Quan D, Kang L, Yang D, Wu H, Yan M, Wu S, Lv L, Zhang G. Guan Y, et al. Among authors: wu h, wu s. Front Pharmacol. 2021 Feb 12;11:575294. doi: 10.3389/fphar.2020.575294. eCollection 2020. Front Pharmacol. 2021. PMID: 33643031 Free PMC article.

8

Geniposide inhibits high glucose-induced cell adhesion through the NF-kappaB signaling pathway in human umbilical vein endothelial cells.

Wang GF, Wu SY, Xu W, Jin H, Zhu ZG, Li ZH, Tian YX, Zhang JJ, Rao JJ, Wu SG. Wang GF, et al. Acta Pharmacol Sin. 2010 Aug;31(8):953-62. doi: 10.1038/aps.2010.83. Acta Pharmacol Sin. 2010. PMID: 20686520 Free PMC article.

9

5-arylalkynyl-2-benzoyl thiophene: a novel microtubule inhibitor exhibits antitumor activity without neurological toxicity.

Zhuang Y, Yang G, Wu S, Chen J, Guo J, Quan D, Zhang T, Yang Z, Tan S, Ji Y, Chen Z, Lv L. Zhuang Y, et al. Among authors: wu s. Am J Cancer Res. 2022 Jan 15;12(1):229-246. eCollection 2022. Am J Cancer Res. 2022. PMID: 35141015 Free PMC article.

10

Genipin inhibits endothelial exocytosis via nitric oxide in cultured human umbilical vein endothelial cells.

Wang GF, Wu SY, Rao JJ, Lü L, Xu W, Pang JX, Liu ZQ, Wu SG, Zhang JJ. Wang GF, et al. Acta Pharmacol Sin. 2009 May;30(5):589-96. doi: 10.1038/aps.2009.31. Epub 2009 Apr 6. Acta Pharmacol Sin. 2009. PMID: 19349964 Free PMC article.

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