Huang HY - Search Results

1

PI3K/Akt/mTOR signaling orchestrates the phenotypic transition and chemo-resistance of small cell lung cancer.

Li X, Li C, Guo C, Zhao Q, Cao J, Huang HY, Yue M, Xue Y, Jin Y, Hu L, Ji H. Li X, et al. Among authors: huang hy. J Genet Genomics. 2021 Jul 20;48(7):640-651. doi: 10.1016/j.jgg.2021.04.001. Epub 2021 Apr 27. J Genet Genomics. 2021. PMID: 34167917

2

Cetuximab-modified mesoporous silica nano-medicine specifically targets EGFR-mutant lung cancer and overcomes drug resistance.

Wang Y, Huang HY, Yang L, Zhang Z, Ji H. Wang Y, et al. Among authors: huang hy. Sci Rep. 2016 May 6;6:25468. doi: 10.1038/srep25468. Sci Rep. 2016. PMID: 27151505 Free PMC article.

3

YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63-GPX2 Axis and ROS Accumulation.

Huang H, Zhang W, Pan Y, Gao Y, Deng L, Li F, Li F, Ma X, Hou S, Xu J, Li P, Li X, Hu G, Li C, Chen H, Zhang L, Ji H. Huang H, et al. Cancer Res. 2017 Nov 1;77(21):5769-5781. doi: 10.1158/0008-5472.CAN-17-0449. Epub 2017 Sep 15. Cancer Res. 2017. PMID: 28916653

4

In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis.

Wu Q, Tian Y, Zhang J, Tong X, Huang H, Li S, Zhao H, Tang Y, Yuan C, Wang K, Fang Z, Gao L, Hu X, Li F, Qin Z, Yao S, Chen T, Chen H, Zhang G, Liu W, Sun Y, Chen L, Wong KK, Ge K, Chen L, Ji H. Wu Q, et al. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E3978-E3986. doi: 10.1073/pnas.1716589115. Epub 2018 Apr 9. Proc Natl Acad Sci U S A. 2018. PMID: 29632194 Free PMC article.

5

Cullin5 deficiency promotes small-cell lung cancer metastasis by stabilizing integrin β1.

Zhao G, Gong L, Su D, Jin Y, Guo C, Yue M, Yao S, Qin Z, Ye Y, Tang Y, Wu Q, Zhang J, Cui B, Ding Q, Huang H, Hu L, Chen Y, Zhang P, Hu G, Chen L, Wong KK, Gao D, Ji H. Zhao G, et al. J Clin Invest. 2019 Mar 1;129(3):972-987. doi: 10.1172/JCI122779. Epub 2019 Jan 28. J Clin Invest. 2019. PMID: 30688657 Free PMC article.

6

Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition.

Gao L, Hu Y, Tian Y, Fan Z, Wang K, Li H, Zhou Q, Zeng G, Hu X, Yu L, Zhou S, Tong X, Huang H, Chen H, Liu Q, Liu W, Zhang G, Zeng M, Zhou G, He Q, Ji H, Chen L. Gao L, et al. Nat Commun. 2019 Apr 10;10(1):1665. doi: 10.1038/s41467-019-09295-7. Nat Commun. 2019. PMID: 30971692 Free PMC article.

7

Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors.

Wang Y, Zhang J, Ren S, Sun D, Huang HY, Wang H, Jin Y, Li F, Zheng C, Yang L, Deng L, Jiang Z, Jiang T, Han X, Hou S, Guo C, Li F, Gao D, Qin J, Gao D, Chen L, Lin SH, Wong KK, Li C, Hu L, Zhou C, Ji H. Wang Y, et al. Among authors: huang hy. Cell Rep. 2019 Jul 9;28(2):512-525.e6. doi: 10.1016/j.celrep.2019.06.026. Cell Rep. 2019. PMID: 31291585 Free article.

8

Keratin 14-high subpopulation mediates lung cancer metastasis potentially through Gkn1 upregulation.

Yao S, Huang HY, Han X, Ye Y, Qin Z, Zhao G, Li F, Hu G, Hu L, Ji H. Yao S, et al. Among authors: huang hy. Oncogene. 2019 Sep;38(36):6354-6369. doi: 10.1038/s41388-019-0889-0. Epub 2019 Jul 18. Oncogene. 2019. PMID: 31320708

9

Specific gut microbiome signature predicts the early-stage lung cancer.

Zheng Y, Fang Z, Xue Y, Zhang J, Zhu J, Gao R, Yao S, Ye Y, Wang S, Lin C, Chen S, Huang H, Hu L, Jiang GN, Qin H, Zhang P, Chen J, Ji H. Zheng Y, et al. Gut Microbes. 2020 Jul 3;11(4):1030-1042. doi: 10.1080/19490976.2020.1737487. Epub 2020 Apr 2. Gut Microbes. 2020. PMID: 32240032 Free PMC article.

10

In vivo miRNA knockout screening identifies miR-190b as a novel tumor suppressor.

Hong H, Yao S, Zhang Y, Ye Y, Li C, Hu L, Sun Y, Huang HY, Ji H. Hong H, et al. Among authors: huang hy. PLoS Genet. 2020 Nov 2;16(11):e1009168. doi: 10.1371/journal.pgen.1009168. eCollection 2020 Nov. PLoS Genet. 2020. PMID: 33137086 Free PMC article.

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