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Syntheses and antimicrobial activities of ogipeptin derivatives.
Takiguchi S, Homma H, Fujisawa T, Hirota-Takahata Y, Ono Y, Kizuka M, Ishii Y, Yoshimura S, Nishi T. Takiguchi S, et al. Among authors: nishi t. Bioorg Med Chem Lett. 2021 Jun 15;42:128093. doi: 10.1016/j.bmcl.2021.128093. Epub 2021 May 6. Bioorg Med Chem Lett. 2021. PMID: 33964447
Practical one-step glucuronidation via biotransformation.
Ohnuki T, Ejiri M, Kizuka M, Fujiwara M, Nishi T. Ohnuki T, et al. Among authors: nishi t. Bioorg Med Chem Lett. 2019 Jan 15;29(2):199-203. doi: 10.1016/j.bmcl.2018.11.056. Epub 2018 Nov 28. Bioorg Med Chem Lett. 2019. PMID: 30551902
Total Synthesis and Structural Elucidation of Ogipeptins.
Takiguchi S, Hirota-Takahata Y, Nishi T. Takiguchi S, et al. Among authors: nishi t. Org Lett. 2022 Jul 15;24(27):4935-4938. doi: 10.1021/acs.orglett.2c01863. Epub 2022 Jul 7. Org Lett. 2022. PMID: 35796660
Synthesis and evaluation of thiomannosides, potent and orally active FimH inhibitors.
Sattigeri JA, Garg M, Bhateja P, Soni A, Rauf ARA, Gupta M, Deshmukh MS, Jain T, Alekar N, Barman TK, Jha P, Chaira T, Bambal RB, Upadhyay DJ, Nishi T. Sattigeri JA, et al. Among authors: nishi t. Bioorg Med Chem Lett. 2018 Sep 15;28(17):2993-2997. doi: 10.1016/j.bmcl.2018.06.017. Epub 2018 Jun 12. Bioorg Med Chem Lett. 2018. PMID: 30017316
Lead optimization of 5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxyhexanamides to reduce a cardiac safety issue: discovery of DS-8108b, an orally active renin inhibitor.
Nakamura Y, Fujimoto T, Ogawa Y, Namiki H, Suzuki S, Asano M, Sugita C, Mochizuki A, Miyazaki S, Tamaki K, Nagai Y, Inoue S, Nagayama T, Kato M, Chiba K, Takasuna K, Nishi T. Nakamura Y, et al. Among authors: nishi t. Bioorg Med Chem. 2013 Jun 1;21(11):3175-96. doi: 10.1016/j.bmc.2013.03.022. Epub 2013 Mar 26. Bioorg Med Chem. 2013. PMID: 23598247
1,122 results