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The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription.
Akay A, Di Domenico T, Suen KM, Nabih A, Parada GE, Larance M, Medhi R, Berkyurek AC, Zhang X, Wedeles CJ, Rudolph KLM, Engelhardt J, Hemberg M, Ma P, Lamond AI, Claycomb JM, Miska EA. Akay A, et al. Among authors: parada ge. Dev Cell. 2017 Aug 7;42(3):241-255.e6. doi: 10.1016/j.devcel.2017.07.002. Dev Cell. 2017. PMID: 28787591 Free PMC article.
Alternative splicing modulation by G-quadruplexes.
Georgakopoulos-Soares I, Parada GE, Wong HY, Medhi R, Furlan G, Munita R, Miska EA, Kwok CK, Hemberg M. Georgakopoulos-Soares I, et al. Among authors: parada ge. Nat Commun. 2022 May 3;13(1):2404. doi: 10.1038/s41467-022-30071-7. Nat Commun. 2022. PMID: 35504902 Free PMC article.
High-throughput characterization of the role of non-B DNA motifs on promoter function.
Georgakopoulos-Soares I, Victorino J, Parada GE, Agarwal V, Zhao J, Wong HY, Umar MI, Elor O, Muhwezi A, An JY, Sanders SJ, Kwok CK, Inoue F, Hemberg M, Ahituv N. Georgakopoulos-Soares I, et al. Among authors: parada ge. Cell Genom. 2022 Apr 13;2(4):100111. doi: 10.1016/j.xgen.2022.100111. Epub 2022 Mar 15. Cell Genom. 2022. PMID: 35573091 Free PMC article.
High-throughput total RNA sequencing in single cells using VASA-seq.
Salmen F, De Jonghe J, Kaminski TS, Alemany A, Parada GE, Verity-Legg J, Yanagida A, Kohler TN, Battich N, van den Brekel F, Ellermann AL, Arias AM, Nichols J, Hemberg M, Hollfelder F, van Oudenaarden A. Salmen F, et al. Among authors: parada ge. Nat Biotechnol. 2022 Dec;40(12):1780-1793. doi: 10.1038/s41587-022-01361-8. Epub 2022 Jun 27. Nat Biotechnol. 2022. PMID: 35760914 Free PMC article.
Secondary structures in RNA synthesis, splicing and translation.
Georgakopoulos-Soares I, Parada GE, Hemberg M. Georgakopoulos-Soares I, et al. Among authors: parada ge. Comput Struct Biotechnol J. 2022 May 27;20:2871-2884. doi: 10.1016/j.csbj.2022.05.041. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35765654 Free PMC article. Review.
19 results