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Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-type and Mutant Colorectal Cancer.
Jiso A, Demuth P, Bachowsky M, Haas M, Seiwert N, Heylmann D, Rasenberger B, Christmann M, Dietrich L, Brunner T, Riyanti, Schäberle TF, Plubrukarn A, Fahrer J. Jiso A, et al. Among authors: seiwert n. Cancers (Basel). 2021 Jun 30;13(13):3282. doi: 10.3390/cancers13133282. Cancers (Basel). 2021. PMID: 34209047 Free PMC article.
Formation of trans-epoxy fatty acids correlates with formation of isoprostanes and could serve as biomarker of oxidative stress.
Rund KM, Heylmann D, Seiwert N, Wecklein S, Oger C, Galano JM, Durand T, Chen R, Gueler F, Fahrer J, Bornhorst J, Schebb NH. Rund KM, et al. Among authors: seiwert n. Prostaglandins Other Lipid Mediat. 2019 Oct;144:106334. doi: 10.1016/j.prostaglandins.2019.04.004. Epub 2019 Apr 19. Prostaglandins Other Lipid Mediat. 2019. PMID: 31009766 Review.
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