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Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis.
Joosse ME, Charbit-Henrion F, Boisgard R, Raatgeep RHC, Lindenbergh-Kortleve DJ, Costes LMM, Nugteren S, Guegan N, Parlato M, Veenbergen S, Malan V, Nowak JK, Hollink IHIM, Mearin ML, Escher JC, Cerf-Bensussan N, Samsom JN. Joosse ME, et al. Among authors: costes lmm. Mucosal Immunol. 2021 Sep;14(5):1172-1182. doi: 10.1038/s41385-021-00423-5. Epub 2021 Jul 5. Mucosal Immunol. 2021. PMID: 34226674 Free PMC article.
Serum Immune Profiling in Paediatric Crohn's Disease Demonstrates Stronger Immune Modulation With First-Line Infliximab Than Conventional Therapy and Pre-Treatment Profiles Predict Clinical Response to Both Treatments.
Jongsma MME, Costes LMM, Tindemans I, Cozijnsen MA, Raatgreep RHC, van Pieterson M, Li Y, Escher JC, de Ridder L, Samsom JN. Jongsma MME, et al. Among authors: costes lmm. J Crohns Colitis. 2023 Aug 21;17(8):1262-1277. doi: 10.1093/ecco-jcc/jjad049. J Crohns Colitis. 2023. PMID: 36934327 Free PMC article. Clinical Trial.
Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease.
Bouziat R, Hinterleitner R, Brown JJ, Stencel-Baerenwald JE, Ikizler M, Mayassi T, Meisel M, Kim SM, Discepolo V, Pruijssers AJ, Ernest JD, Iskarpatyoti JA, Costes LM, Lawrence I, Palanski BA, Varma M, Zurenski MA, Khomandiak S, McAllister N, Aravamudhan P, Boehme KW, Hu F, Samsom JN, Reinecker HC, Kupfer SS, Guandalini S, Semrad CE, Abadie V, Khosla C, Barreiro LB, Xavier RJ, Ng A, Dermody TS, Jabri B. Bouziat R, et al. Science. 2017 Apr 7;356(6333):44-50. doi: 10.1126/science.aah5298. Science. 2017. PMID: 28386004 Free PMC article.
IL22/IL-22R pathway induces cell survival in human glioblastoma cells.
Akil H, Abbaci A, Lalloué F, Bessette B, Costes LM, Domballe L, Charreau S, Guilloteau K, Karayan-Tapon L, Bernard FX, Morel F, Jauberteau MO, Lecron JC. Akil H, et al. PLoS One. 2015 Mar 20;10(3):e0119872. doi: 10.1371/journal.pone.0119872. eCollection 2015. PLoS One. 2015. PMID: 25793261 Free PMC article.
Neural networks in intestinal immunoregulation.
Costes LM, Boeckxstaens GE, de Jonge WJ, Cailotto C. Costes LM, et al. Organogenesis. 2013 Jul-Sep;9(3):216-23. doi: 10.4161/org.25646. Epub 2013 Jul 18. Organogenesis. 2013. PMID: 23867810 Free PMC article. Review.
Gut-homing and intestinal TIGITnegCD38+ memory T cells acquire an IL-12-induced, ex-Th17 pathogenic phenotype in a subgroup of Crohn's disease patients with a severe disease course.
Heredia M, Barendregt DMH, Tindemans I, Klomberg RCW, Aardoom MA, Calado B, Costes LMM, Joosse ME, Hulleman-van Haaften DH, Tuk B, van Berkel LA, Kemos P, Ruemmele FM, Croft NM, Escher JC, de Ridder L, Samsom JN. Heredia M, et al. Among authors: costes lmm. Mucosal Immunol. 2024 Nov 24:S1933-0219(24)00116-8. doi: 10.1016/j.mucimm.2024.11.008. Online ahead of print. Mucosal Immunol. 2024. PMID: 39586377 Free article.
The Biodistribution of the Spike Protein after Ad26.COV2.S Vaccination Is Unlikely to Play a Role in Vaccine-Induced Immune Thrombotic Thrombocytopenia.
Marquez-Martinez S, Khan S, Lubbe JV, Solforosi L, Costes LMM, Choi Y, Boedhoe S, Verslegers M, Heerden MV, Roosen W, Jonghe S, Kristyanto H, Rezelj V, Hendriks J, Serroyen J, Tolboom J, Wegmann F, Zahn RC. Marquez-Martinez S, et al. Among authors: costes lmm. Vaccines (Basel). 2024 May 20;12(5):559. doi: 10.3390/vaccines12050559. Vaccines (Basel). 2024. PMID: 38793810 Free PMC article.
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