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Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning.
Echle A, Grabsch HI, Quirke P, van den Brandt PA, West NP, Hutchins GGA, Heij LR, Tan X, Richman SD, Krause J, Alwers E, Jenniskens J, Offermans K, Gray R, Brenner H, Chang-Claude J, Trautwein C, Pearson AT, Boor P, Luedde T, Gaisa NT, Hoffmeister M, Kather JN. Echle A, et al. Among authors: tan x. Gastroenterology. 2020 Oct;159(4):1406-1416.e11. doi: 10.1053/j.gastro.2020.06.021. Epub 2020 Jun 17. Gastroenterology. 2020. PMID: 32562722 Free PMC article.
Nerve fibers in the tumor microenvironment in neurotropic cancer-pancreatic cancer and cholangiocarcinoma.
Tan X, Sivakumar S, Bednarsch J, Wiltberger G, Kather JN, Niehues J, de Vos-Geelen J, Valkenburg-van Iersel L, Kintsler S, Roeth A, Hao G, Lang S, Coolsen ME, den Dulk M, Aberle MR, Koolen J, Gaisa NT, Olde Damink SWM, Neumann UP, Heij LR. Tan X, et al. Oncogene. 2021 Feb;40(5):899-908. doi: 10.1038/s41388-020-01578-4. Epub 2020 Dec 7. Oncogene. 2021. PMID: 33288884 Free PMC article. Review.
Nerve Fibers in the Tumor Microenvironment Are Co-Localized with Lymphoid Aggregates in Pancreatic Cancer.
Heij LR, Tan X, Kather JN, Niehues JM, Sivakumar S, Heussen N, van der Kroft G, Damink SWMO, Lang S, Aberle MR, Luedde T, Gaisa NT, Bednarsch J, Liu DHW, Cleutjens JPM, Modest DP, Neumann UP, Wiltberger GJ. Heij LR, et al. Among authors: tan x. J Clin Med. 2021 Jan 30;10(3):490. doi: 10.3390/jcm10030490. J Clin Med. 2021. PMID: 33573277 Free PMC article.
The Presence of Small Nerve Fibers in the Tumor Microenvironment as Predictive Biomarker of Oncological Outcome Following Partial Hepatectomy for Intrahepatic Cholangiocarcinoma.
Bednarsch J, Tan X, Czigany Z, Liu D, Lang SA, Sivakumar S, Kather JN, Appinger S, Rosin M, Boroojerdi S, Dahl E, Gaisa NT, den Dulk M, Coolsen M, Ulmer TF, Neumann UP, Heij LR. Bednarsch J, et al. Among authors: tan x. Cancers (Basel). 2021 Jul 21;13(15):3661. doi: 10.3390/cancers13153661. Cancers (Basel). 2021. PMID: 34359564 Free PMC article.
Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort study.
Muti HS, Heij LR, Keller G, Kohlruss M, Langer R, Dislich B, Cheong JH, Kim YW, Kim H, Kook MC, Cunningham D, Allum WH, Langley RE, Nankivell MG, Quirke P, Hayden JD, West NP, Irvine AJ, Yoshikawa T, Oshima T, Huss R, Grosser B, Roviello F, d'Ignazio A, Quaas A, Alakus H, Tan X, Pearson AT, Luedde T, Ebert MP, Jäger D, Trautwein C, Gaisa NT, Grabsch HI, Kather JN. Muti HS, et al. Among authors: tan x. Lancet Digit Health. 2021 Oct;3(10):e654-e664. doi: 10.1016/S2589-7500(21)00133-3. Epub 2021 Aug 17. Lancet Digit Health. 2021. PMID: 34417147 Free PMC article.
PD-1+ T-Cells Correlate with Nerve Fiber Density as a Prognostic Biomarker in Patients with Resected Perihilar Cholangiocarcinoma.
Tan X, Bednarsch J, Rosin M, Appinger S, Liu D, Wiltberger G, Garcia Vallejo J, Lang SA, Czigany Z, Boroojerdi S, Gaisa NT, Boor P, Bülow RD, De Vos-Geelen J, Valkenburg-van Iersel L, Clahsen-van Groningen MC, de Jong EJM, Groot Koerkamp B, Doukas M, Rocha FG, Luedde T, Klinge U, Sivakumar S, Neumann UP, Heij LR. Tan X, et al. Cancers (Basel). 2022 Apr 27;14(9):2190. doi: 10.3390/cancers14092190. Cancers (Basel). 2022. PMID: 35565318 Free PMC article.
Expression of Checkpoint Molecules in the Tumor Microenvironment of Intrahepatic Cholangiocarcinoma: Implications for Immune Checkpoint Blockade Therapy.
Heij L, Bednarsch J, Tan X, Rosin M, Appinger S, Reichel K, Pecina D, Doukas M, van Dam RM, Garcia Vallejo J, Ulmer F, Lang S, Luedde T, Rocha FG, Sivakumar S, Neumann UP. Heij L, et al. Among authors: tan x. Cells. 2023 Mar 9;12(6):851. doi: 10.3390/cells12060851. Cells. 2023. PMID: 36980192 Free PMC article.
9,436 results