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The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
Oncogene. 2021 Aug;40(34):5286-5301. doi: 10.1038/s41388-021-01917-z. Epub 2021 Jul 10.
Oncogene. 2021.
PMID: 34247190
Free PMC article.
Impact of mutant β-catenin on ABCB1 expression and therapy response in colon cancer cells.
Stein U, Fleuter C, Siegel F, Smith J, Kopacek A, Scudiero DA, Hite KM, Schlag PM, Shoemaker RH, Walther W.
Stein U, et al. Among authors: fleuter c.
Br J Cancer. 2012 Apr 10;106(8):1395-405. doi: 10.1038/bjc.2012.81. Epub 2012 Mar 29.
Br J Cancer. 2012.
PMID: 22460269
Free PMC article.
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