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PCSK9 deficiency rewires heart metabolism and drives heart failure with preserved ejection fraction.
Da Dalt L, Castiglioni L, Baragetti A, Audano M, Svecla M, Bonacina F, Pedretti S, Uboldi P, Benzoni P, Giannetti F, Barbuti A, Pellegatta F, Indino S, Donetti E, Sironi L, Mitro N, Catapano AL, Norata GD. Da Dalt L, et al. Among authors: sironi l. Eur Heart J. 2021 Aug 21;42(32):3078-3090. doi: 10.1093/eurheartj/ehab431. Eur Heart J. 2021. PMID: 34252181 Free PMC article.
Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, increases survival in stroke-prone rats by preventing systemic inflammation and endothelial dysfunction: comparison with aspirin and rosuvastatin.
Gelosa P, Ballerio R, Banfi C, Nobili E, Gianella A, Pignieri A, Brioschi M, Guerrini U, Castiglioni L, Blanc-Guillemaud V, Lerond L, Tremoli E, Sironi L. Gelosa P, et al. Among authors: sironi l. J Pharmacol Exp Ther. 2010 Jul;334(1):199-205. doi: 10.1124/jpet.110.165787. Epub 2010 Mar 23. J Pharmacol Exp Ther. 2010. PMID: 20332187
Peroxisome proliferator-activated receptor {alpha} agonism prevents renal damage and the oxidative stress and inflammatory processes affecting the brains of stroke-prone rats.
Gelosa P, Banfi C, Gianella A, Brioschi M, Pignieri A, Nobili E, Castiglioni L, Cimino M, Tremoli E, Sironi L. Gelosa P, et al. Among authors: sironi l. J Pharmacol Exp Ther. 2010 Nov;335(2):324-31. doi: 10.1124/jpet.110.171090. Epub 2010 Jul 29. J Pharmacol Exp Ther. 2010. PMID: 20671072
Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, prevents hypertensive vascular hypertrophy and fibrosis.
Gelosa P, Sevin G, Pignieri A, Budelli S, Castiglioni L, Blanc-Guillemaud V, Lerond L, Tremoli E, Sironi L. Gelosa P, et al. Among authors: sironi l. Am J Physiol Heart Circ Physiol. 2011 Mar;300(3):H762-8. doi: 10.1152/ajpheart.00880.2010. Epub 2010 Dec 10. Am J Physiol Heart Circ Physiol. 2011. PMID: 21148758 Free article.
195 results