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WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis.
Brandenburg J, Marwitz S, Tazoll SC, Waldow F, Kalsdorf B, Vierbuchen T, Scholzen T, Gross A, Goldenbaum S, Hölscher A, Hein M, Linnemann L, Reimann M, Kispert A, Leitges M, Rupp J, Lange C, Niemann S, Behrends J, Goldmann T, Heine H, Schaible UE, Hölscher C, Schwudke D, Reiling N. Brandenburg J, et al. Among authors: holscher c, holscher a. J Clin Invest. 2021 Aug 16;131(16):e141833. doi: 10.1172/JCI141833. J Clin Invest. 2021. PMID: 34255743 Free PMC article.
Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9.
Hölscher C, Reiling N, Schaible UE, Hölscher A, Bathmann C, Korbel D, Lenz I, Sonntag T, Kröger S, Akira S, Mossmann H, Kirschning CJ, Wagner H, Freudenberg M, Ehlers S. Hölscher C, et al. Among authors: holscher a. Eur J Immunol. 2008 Mar;38(3):680-94. doi: 10.1002/eji.200736458. Eur J Immunol. 2008. PMID: 18266299 Free article.
The increased protection and pathology in Mycobacterium tuberculosis-infected IL-27R-alpha-deficient mice is supported by IL-17A and is associated with the IL-17A-induced expansion of multifunctional T cells.
Erdmann H, Behrends J, Ritter K, Hölscher A, Volz J, Rosenkrands I, Hölscher C. Erdmann H, et al. Among authors: holscher c, holscher a. Mucosal Immunol. 2018 Jul;11(4):1168-1180. doi: 10.1038/s41385-018-0026-3. Epub 2018 May 4. Mucosal Immunol. 2018. PMID: 29728641 Free article.
Interleukin-23 instructs protective multifunctional CD4 T cell responses after immunization with the Mycobacterium tuberculosis subunit vaccine H1 DDA/TDB independently of interleukin-17A.
Ritter K, Behrends J, Erdmann H, Rousseau J, Hölscher A, Volz J, Prinz I, Lindenstrøm T, Hölscher C. Ritter K, et al. Among authors: holscher c, holscher a. J Mol Med (Berl). 2021 Nov;99(11):1585-1602. doi: 10.1007/s00109-021-02100-3. Epub 2021 Aug 5. J Mol Med (Berl). 2021. PMID: 34351501 Free PMC article.
Interleukin-13-Overexpressing Mice Represent an Advanced Preclinical Model for Detecting the Distribution of Antimycobacterial Drugs within Centrally Necrotizing Granulomas.
Walter K, Kokesch-Himmelreich J, Treu A, Waldow F, Hillemann D, Jakobs N, Lemm AK, Schwudke D, Römpp A, Hölscher C. Walter K, et al. Among authors: holscher c. Antimicrob Agents Chemother. 2022 Jun 21;66(6):e0158821. doi: 10.1128/AAC.01588-21. Epub 2021 Dec 6. Antimicrob Agents Chemother. 2022. PMID: 34871095 Free PMC article.
430 results