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Competitive binding of extracellular accumulated heparan sulfate reduces lysosomal storage defects and triggers neuronal differentiation in a model of Mucopolysaccharidosis IIIB.
De Pasquale V, Scerra G, Scarcella M, D'Agostino M, Pavone LM. De Pasquale V, et al. Among authors: scerra g. Biochim Biophys Acta Mol Cell Res. 2021 Oct;1868(11):119113. doi: 10.1016/j.bbamcr.2021.119113. Epub 2021 Jul 28. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 34329663 Free article.
Lysosomal positioning diseases: beyond substrate storage.
Scerra G, De Pasquale V, Scarcella M, Caporaso MG, Pavone LM, D'Agostino M. Scerra G, et al. Open Biol. 2022 Oct;12(10):220155. doi: 10.1098/rsob.220155. Epub 2022 Oct 26. Open Biol. 2022. PMID: 36285443 Free PMC article. Review.
N-Substituted l-Iminosugars for the Treatment of Sanfilippo Type B Syndrome.
De Pasquale V, Esposito A, Scerra G, Scarcella M, Ciampa M, Luongo A, D'Alonzo D, Guaragna A, D'Agostino M, Pavone LM. De Pasquale V, et al. Among authors: scerra g. J Med Chem. 2023 Feb 9;66(3):1790-1808. doi: 10.1021/acs.jmedchem.2c01617. Epub 2023 Jan 25. J Med Chem. 2023. PMID: 36696678 Free PMC article.
The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein.
Bonavita R, Scerra G, Di Martino R, Nuzzo S, Polishchuk E, Di Gennaro M, Williams SV, Caporaso MG, Caiazza C, Polishchuk R, D'Agostino M, Fleming A, Renna M. Bonavita R, et al. Among authors: scerra g. Hum Mol Genet. 2023 Jul 4;32(14):2269-2291. doi: 10.1093/hmg/ddad047. Hum Mol Genet. 2023. PMID: 36971475 Free PMC article.
PTEN deficiency leads to proteasome addiction: a novel vulnerability in glioblastoma.
Benitez JA, Finlay D, Castanza A, Parisian AD, Ma J, Longobardi C, Campos A, Vadla R, Izurieta A, Scerra G, Koga T, Long T, Chavez L, Mesirov JP, Vuori K, Furnari F. Benitez JA, et al. Among authors: scerra g. Neuro Oncol. 2021 Jul 1;23(7):1072-1086. doi: 10.1093/neuonc/noab001. Neuro Oncol. 2021. PMID: 33428749 Free PMC article.
A method for the analysis of the oligomerization profile of the Huntington's disease-associated, aggregation-prone mutant huntingtin protein by isopycnic ultracentrifugation.
Bonavita R, Di Martino R, Cortone G, Prodomo A, Di Gennaro M, Scerra G, Panico V, Nuzzo S, Salvatore M, Williams SV, Vitale F, Caporaso MG, D'Agostino M, Pisani FM, Fleming A, Renna M. Bonavita R, et al. Among authors: scerra g. Front Mol Biosci. 2024 Jun 27;11:1420691. doi: 10.3389/fmolb.2024.1420691. eCollection 2024. Front Mol Biosci. 2024. PMID: 38993838 Free PMC article.
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