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Page 1
Tumor burden limits bispecific antibody efficacy through T cell exhaustion averted by concurrent cytotoxic therapy.
Meermeier EW, Welsh SJ, Sharik ME, Du MT, Garbitt VM, Riggs DL, Shi CX, Stein CK, Bergsagel M, Chau B, Wheeler ML, Bezman N, Wang F, Strop P, Bergsagel PL, Chesi M. Meermeier EW, et al. Among authors: strop p. Blood Cancer Discov. 2021 Jul;2(4):354-369. doi: 10.1158/2643-3230.BCD-21-0038. Blood Cancer Discov. 2021. PMID: 34258584 Free PMC article.
Preclinical Efficacy and Safety Comparison of CD3 Bispecific and ADC Modalities Targeting BCMA for the Treatment of Multiple Myeloma.
Panowski SH, Kuo TC, Zhang Y, Chen A, Geng T, Aschenbrenner L, Kamperschroer C, Pascua E, Chen W, Delaria K, Farias S, Bateman M, Dushin RG, Chin SM, Van Blarcom TJ, Yeung YA, Lindquist KC, Chunyk AG, Kuang B, Han B, Mirsky M, Pardo I, Buetow B, Martin TG, Wolf JL, Shelton D, Rajpal A, Strop P, Chaparro-Riggers J, Sasu BJ. Panowski SH, et al. Among authors: strop p. Mol Cancer Ther. 2019 Nov;18(11):2008-2020. doi: 10.1158/1535-7163.MCT-19-0007. Epub 2019 Aug 21. Mol Cancer Ther. 2019. PMID: 31434693
Integrated Approach for Characterizing Bispecific Antibody/Antigens Complexes and Mapping Binding Epitopes with SEC/MALS, Native Mass Spectrometry, and Protein Footprinting.
Huang RY, Wang F, Wheeler M, Wang Y, Langish R, Chau B, Dong J, Morishige W, Bezman N, Strop P, Rajpal A, Gudmundsson O, Chen G. Huang RY, et al. Among authors: strop p. Anal Chem. 2020 Aug 4;92(15):10709-10716. doi: 10.1021/acs.analchem.0c01876. Epub 2020 Jul 22. Anal Chem. 2020. PMID: 32639723
[No title available]
[No authors listed] [No authors listed] PMID: 34236997
Antibody blockade of CD96 by distinct molecular mechanisms.
Lee PS, Chau B, Barman I, Bee C, Jashnani A, Hogan JM, Aguilar B, Dollinger G, Rajpal A, Strop P. Lee PS, et al. Among authors: strop p. MAbs. 2021 Jan-Dec;13(1):1979800. doi: 10.1080/19420862.2021.1979800. MAbs. 2021. PMID: 34595996 Free PMC article.
Improved therapeutic index of an acidic pH-selective antibody.
Lee PS, MacDonald KG, Massi E, Chew PV, Bee C, Perkins P, Chau B, Thudium K, Lohre J, Nandi P, Deyanova EG, Barman I, Gudmundsson O, Dollinger G, Sproul T, Engelhardt JJ, Strop P, Rajpal A. Lee PS, et al. Among authors: strop p. MAbs. 2022 Jan-Dec;14(1):2024642. doi: 10.1080/19420862.2021.2024642. MAbs. 2022. PMID: 35192429 Free PMC article.
Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo model.
Zorn JA, Wheeler ML, Barnes RM, Kaberna J, Morishige W, Harris M, Huang RY, Lohre J, Chang YC, Chau B, Powers K, Schindler I, Neradugomma N, Thomas W, Liao X, Zhou Y, West SM, Wang F, Kotapati S, Chen G, Yamazoe S, Kosenko A, Dollinger G, Sproul T, Rajpal A, Strop P. Zorn JA, et al. Among authors: strop p. Sci Rep. 2022 Mar 3;12(1):3530. doi: 10.1038/s41598-022-06953-7. Sci Rep. 2022. PMID: 35241687 Free PMC article.
Targeting CLDN18.2 by CD3 Bispecific and ADC Modalities for the Treatments of Gastric and Pancreatic Cancer.
Zhu G, Foletti D, Liu X, Ding S, Melton Witt J, Hasa-Moreno A, Rickert M, Holz C, Aschenbrenner L, Yang AH, Kraynov E, Evering W, Obert L, Lee C, Sai T, Mistry T, Lindquist KC, Van Blarcom T, Strop P, Chaparro-Riggers J, Liu SH. Zhu G, et al. Among authors: strop p. Sci Rep. 2019 Jun 10;9(1):8420. doi: 10.1038/s41598-019-44874-0. Sci Rep. 2019. PMID: 31182754 Free PMC article.
127 results