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A loss-of-function variant in SUV39H2 identified in autism-spectrum disorder causes altered H3K9 trimethylation and dysregulation of protocadherin β-cluster genes in the developing brain.
Balan S, Iwayama Y, Ohnishi T, Fukuda M, Shirai A, Yamada A, Weirich S, Schuhmacher MK, Dileep KV, Endo T, Hisano Y, Kotoshiba K, Toyota T, Otowa T, Kuwabara H, Tochigi M, Watanabe A, Ohba H, Maekawa M, Toyoshima M, Sasaki T, Nakamura K, Tsujii M, Matsuzaki H, Zhang KYJ, Jeltsch A, Shinkai Y, Yoshikawa T. Balan S, et al. Among authors: dileep kv. Mol Psychiatry. 2021 Dec;26(12):7550-7559. doi: 10.1038/s41380-021-01199-7. Epub 2021 Jul 15. Mol Psychiatry. 2021. PMID: 34262135
EC330, a small-molecule compound, is a potential novel inhibitor of LIF signaling.
Yue X, Wu F, Wang J, Kim K, Santhamma B, Dileep KV, Zhang KYJ, Viswanadhapalli S, Vadlamudi RK, Ahmed G, Feng Z, Nickisch K, Hu W. Yue X, et al. Among authors: dileep kv. J Mol Cell Biol. 2020 Jul 3;12(6):477-480. doi: 10.1093/jmcb/mjaa008. J Mol Cell Biol. 2020. PMID: 32221559 Free PMC article. No abstract available.
Targeting LIF/LIFR signaling in cancer.
Viswanadhapalli S, Dileep KV, Zhang KYJ, Nair HB, Vadlamudi RK. Viswanadhapalli S, et al. Among authors: dileep kv. Genes Dis. 2021 Apr 29;9(4):973-980. doi: 10.1016/j.gendis.2021.04.003. eCollection 2022 Jul. Genes Dis. 2021. PMID: 35685476 Free PMC article. Review.
45 results